ICA Kit ELISA
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- Antigène Voir toutes ICA Kits ELISA
- ICA (Islet Cell Antibody (ICA))
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Reactivité
- Humain
- Méthode de détection
- Colorimetric
- Application
- ELISA
- Type d'échantillon
- Serum
- Sensibilité
- n/a
- Attributs du produit
- Type 1 diabetes, also known as insulin-dependent diabetes mellitus (IDDM), results from a chronic autoimmune process which destructs the insulin-secreting pancreatic beta cells. This is caused by simultaneous action of specific auto-reactive CD4+ and CD8+ T lymphocytes. Even before the onset of type 1 diabetes autoantibodies against different antigens of the islet cells can be detected in the serum of those patients. This process may take years to complete and may occur at any time at all ages.
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Volume d'échantillon
- 50 μL
- Plaque
- Pre-coated
- Protocole
- The ICA Screen ELISA Assay Kit system uses the ability of IC autoantibodies to act di-valently, that is, to form a bridge between autoantigens (highly purified material from primate source) coated onto the plate and liquid phase autoantigen-Biotin. In the first step IC autoantibodies from the sample bind to autoantigens coated on the microtiter plate. In a second step IC-autoantigen-Biotin binds to this complex which correlates with the amount of IC autoantibodies in patient's serum. Unbound IC-autoantigen-Biotin is removed by washing.
- Restrictions
- For Research Use only
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- Stock
- 4 °C
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- Antigène Voir toutes ICA Kits ELISA
- ICA (Islet Cell Antibody (ICA))
- Autre désignation
- ICA (Islet Cell Antibody) (ICA Produits)
- Synonymes
- PICA Kit ELISA, Ica Kit ELISA, mICA Kit ELISA, transferrin Kit ELISA, RIKEN cDNA 1300017J02 gene Kit ELISA, TF Kit ELISA, 1300017J02Rik Kit ELISA
- Classe de substances
- Antibody
- Pathways
- Transition Metal Ion Homeostasis
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