EGF Kit ELISA
Aperçu rapide pour EGF Kit ELISA (ABIN5068374)
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Méthode de détection
Type de méthode
Application
Type d'échantillon
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Sensibilité
- > 20 pg/mL
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Attributs du produit
- Epidermal Growth Factor, Human (EGF), ELISA Kit
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Ingrédients
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- Microtiter Plate 1x96wells
- . EGF (HRP) 1x15ml
- * EGF Standard 2x4ng
- Calibrator Diluent I (serum/plasma) 1x22ml
- Calibrator Diluent II (cell culture supernatant/urine) 1x22ml
- Wash Buffer (20X) 1x60ml
- Substrate A 1x11ml
- . Substrate B 1x11ml
- Stop Solution, O4, 1x14ml
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Restrictions
- For Research Use only
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- 4°C/-20°C
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- EGF (Epidermal Growth Factor (EGF))
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Autre désignation
- Epidermal Growth Factor
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Sujet
- Epidermal growth factor (EGF), a polypeptide mitogen, was first observed in 1959 by Cohen and Levi-Montalcini while studying Nerve Growth Factor (NGF) in snake venom extracts.1 It was subsequently isolated and purified from mouse submandibular glands. When injected into new-born mice this new factor caused precocious eyelid opening and incisor eruption.2,3 EGF was further purified, based on its ability to induce the proliferation of basal skin cells.4 Also, a potent inhibitor of gastric acid secretion was identified and isolated from the urine of a pregnant women, and named human ß-urogastrone. It was shown that this protein was very similar to purified human EGF.5,6
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Pathways
- Signalisation NF-kappaB, Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Protein targeting to Nucleus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation
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