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SPINT2 Kit ELISA

SPINT2 Reactivité: Humain AA 1-197 Colorimetric Sandwich ELISA
N° du produit ABIN5510588
  • Antigène Voir toutes SPINT2 Kits ELISA
    SPINT2 (serine Peptidase Inhibitor, Kunitz Type, 2 (SPINT2))
    Épitope
    AA 1-197
    Reactivité
    • 3
    • 2
    Humain
    Méthode de détection
    Colorimetric
    Type de méthode
    Sandwich ELISA
    Application
    ELISA
    Fonction
    Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human HAI-2/SPINT2
    Marque
    PicoKine™
    Analytical Method
    Quantitative
    Specificité
    Expression system for standard: NSO
    Immunogen sequence: M1-K197
    Réactivité croisée (Details)
    There is no detectable cross-reactivity with other relevant proteins.
    Attributs du produit

    Tissue Specificity: Expressed in placenta, kidney, pancreas, prostate, testis, thymus, and trachea.

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  • Plaque
    Pre-coated
    Restrictions
    For Research Use only
  • Stock
    4 °C,-20 °C
    Stockage commentaire
    Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
    Date de péremption
    12 months
  • Antigène Voir toutes SPINT2 Kits ELISA
    SPINT2 (serine Peptidase Inhibitor, Kunitz Type, 2 (SPINT2))
    Autre désignation
    SPINT2 (SPINT2 Produits)
    Synonymes
    HAI-2 Kit ELISA, Pb Kit ELISA, DIAR3 Kit ELISA, HAI2 Kit ELISA, Kop Kit ELISA, PB Kit ELISA, AL024025 Kit ELISA, C76321 Kit ELISA, serine peptidase inhibitor, Kunitz type, 2 Kit ELISA, serine peptidase inhibitor, Kunitz type 2 Kit ELISA, serine protease inhibitor, Kunitz type 2 Kit ELISA, Spint2 Kit ELISA, SPINT2 Kit ELISA
    Sujet

    Protein Function: Inhibitor of HGF activator. Also inhibits plasmin, plasma and tissue kallikrein, and factor XIa.

    Background: Kunitz-type protease inhibitor 2 is an enzyme inhibitor that in humans is encoded by the SPINT2 gene. This gene encodes a transmembrane protein with two extracellular Kunitz domains that inhibits a variety of serine proteases. The protein inhibits HGF activator which prevents the formation of active hepatocyte growth factor. And this gene is a putative tumor suppressor, and mutations in this gene result in congenital sodium diarrhea. Multiple transcript variants encoding different isoforms have been found for this gene.

    Synonyms: Kunitz-type protease inhibitor 2,Hepatocyte growth factor activator inhibitor type 2,HAI-2,Placental bikunin,SPINT2,HAI2, KOP,

    Full Gene Name: Kunitz-type protease inhibitor 2

    Cellular Localisation: Membrane, Single-pass type I membrane protein.
    UniProt
    O43291
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