LAMTOR1 Produits
(Late Endosomal/lysosomal Adaptor, MAPK and mTOR Activator 1 (LAMTOR1))
Catégories
Regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factors, energy levels, and amino acids. As part of the Ragulator complex, recruits the Rag GTPases and the mTORC1 complex to lysosomes, a key step in activation of the TOR signaling cascade by amino acids. Directly responsible for anchoring the Ragulator complex to membranes. Also required for late endosomes/lysosomes biogenesis it may regulate both the recycling of receptors through endosomes and the MAPK signaling pathway through recruitment of some of its components to late endosomes. May be involved in cholesterol homeostasis regulating LDL uptake and cholesterol release from late endosomes/lysosomes. May also play a role in RHOA activation (By similarity).
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Catégories LAMTOR1 en vedette
LAMTOR1 Anticorps
High quality antibodies with extensive validation data.
LAMTOR1 Kits ELISA
Reliable ELISA kits for a wide range of species.
LAMTOR1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
LAMTOR1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IF, IHC
Validations
- (3)
N° du produit
ABIN6143083
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
IF, ELISA, IHC
Validations
- (2)
N° du produit
ABIN7167068
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
Validations
N° du produit
ABIN7167070
Quantité
100 μg
Fiche technique
Fiche technique
LAMTOR1 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6968205
Quantité
96 tests
Fiche technique
Fiche technique
LAMTOR1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN3093667
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN3128237
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Rat
Source
Yeast
Validations
N° du produit
ABIN1674349
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits LAMTOR1
: "LAMTOR2/LAMTOR1 complex is required for TAX1BP1-mediated xenophagy." dans: Cellular microbiology, Vol. 21, Issue 4, pp. e12981, (2019) (PubMed).: "mTOR activates the VPS34-UVRAG complex to regulate autolysosomal tubulation and cell survival." dans: The EMBO journal, Vol. 34, Issue 17, pp. 2272-90, (2015) (PubMed).
: "The late endosomal adaptor p14 is a macrophage host-defense factor against Salmonella infection." dans: Journal of cell science, Vol. 125, Issue Pt 11, pp. 2698-708, (2012) (PubMed).
: "MTORC1 functions as a transcriptional regulator of autophagy by preventing nuclear transport of TFEB." dans: Autophagy, Vol. 8, Issue 6, pp. 903-14, (2012) (PubMed).
: "Proteomic analysis of endosomes from genetically modified p14/MP1 mouse embryonic fibroblasts." dans: Proteomics, Vol. 10, Issue 22, pp. 4117-27, (2010) (PubMed).
Synonymes et noms alternatifs relatifs à LAMTOR1
late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 (LAMTOR1), late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 (Lamtor1), late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 S homeolog (lamtor1.S), 2400001E08Rik, C11orf59, c11orf59, C15H11orf59, flj20625, p18, p27RF-Rho, p27rf-rho, PDRO, Pdro, pdro, Ragulator1, ragulator1Protein level used designations for LAMTOR1
- RhoA activator C11orf59
- late endosomal/lysosomal adaptor and MAPK and MTOR activator 1
- lipid raft adaptor protein p18
- p27Kip1-releasing factor from RhoA
- p27kip1 releasing factor from RhoA
- protein associated with DRMs and endosomes
- ragulator complex protein LAMTOR1
- ragulator complex protein PDRO
- RhoA activator C11orf59 homolog
- p27RF-Rho
- rhoA activator C11orf59 homolog
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