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LARP6 Produits

(La Ribonucleoprotein Domain Family, Member 6 (LARP6))

Catégories

Regulates the coordinated translation of type I collagen alpha-1 and alpha-2 mRNAs, CO1A1 and CO1A2. Stabilizes mRNAs through high-affinity binding of a stem-loop structure in their 5' UTR. This regulation requires VIM and MYH10 filaments, and the helicase DHX9 (By similarity).

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Catégories LARP6 en vedette

LARP6 Anticorps

High quality antibodies with extensive validation data.

LARP6 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

LARP6 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, FACS, IHC (p)
Validations
  • (3)
N° du produit ABIN654784
Quantité 400 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IF
Validations
  • (8)
  • (2)
N° du produit ABIN527496
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Application ELISA, IHC
Validations
  • (2)
N° du produit ABIN7157812
Quantité 100 μg
Fiche technique Fiche technique

LARP6 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1309158
Quantité 25 μg
Fiche technique Fiche technique
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN3125075
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3082738
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits LARP6

Blackstock, Higashi, Sukhanov, Shai, Stefanovic, Tabony, Yoshida, Delafontaine: "Insulin-like growth factor-1 increases synthesis of collagen type I via induction of the mRNA-binding protein LARP6 expression and binding to the 5' stem-loop of COL1a1 and COL1a2 mRNA." dans: The Journal of biological chemistry, Vol. 289, Issue 11, pp. 7264-74, (2014) (PubMed).

Wang, Stefanovic: "Role of LARP6 and nonmuscle myosin in partitioning of collagen mRNAs to the ER membrane." dans: PLoS ONE, Vol. 9, Issue 10, pp. e108870, (2014) (PubMed).

Manojlovic, Blackmon, Stefanovic: "Tacrolimus (FK506) prevents early stages of ethanol induced hepatic fibrosis by targeting LARP6 dependent mechanism of collagen synthesis." dans: PLoS ONE, Vol. 8, Issue 6, pp. e65897, (2013) (PubMed).

Vukmirovic, Manojlovic, Stefanovic: "Serine-threonine kinase receptor-associated protein (STRAP) regulates translation of type I collagen mRNAs." dans: Molecular and cellular biology, Vol. 33, Issue 19, pp. 3893-906, (2013) (PubMed).

Manojlovic, Stefanovic: "A novel role of RNA helicase A in regulation of translation of type I collagen mRNAs." dans: RNA (New York, N.Y.), Vol. 18, Issue 2, pp. 321-34, (2012) (PubMed).

Challa, Stefanovic: "A novel role of vimentin filaments: binding and stabilization of collagen mRNAs." dans: Molecular and cellular biology, Vol. 31, Issue 18, pp. 3773-89, (2011) (PubMed).

Cai, Fritz, Stefanovic, Stefanovic: "Binding of LARP6 to the conserved 5' stem-loop regulates translation of mRNAs encoding type I collagen." dans: Journal of molecular biology, Vol. 395, Issue 2, pp. 309-26, (2010) (PubMed).

Cai, Fritz, Stefanovic, Stefanovic: "Nonmuscle myosin-dependent synthesis of type I collagen." dans: Journal of molecular biology, Vol. 401, Issue 4, pp. 564-78, (2010) (PubMed).

Synonymes et noms alternatifs relatifs à LARP6

La ribonucleoprotein domain family, member 6b (larp6b), La ribonucleoprotein domain family member 6 (LARP6), La ribonucleoprotein domain family, member 6 (Larp6), 5430431G03Rik, ACHN, Achn, AI552438, im:7142825, RGD1308414, wu:fa55b04

Protein level used designations for LARP6

  • La ribonucleoprotein domain family, member 6
  • acheron
  • death-associated LA motif protein
  • la-related protein 6
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