LATS2 Produits
(LATS, Large Tumor Suppressor, Homolog 2 (Drosophila) (LATS2))
Catégories
This gene encodes a serine/threonine protein kinase belonging to the LATS tumor suppressor family. The protein localizes to centrosomes during interphase, and early and late metaphase. It interacts with the centrosomal proteins aurora-A and ajuba and is required for accumulation of gamma-tubulin and spindle formation at the onset of mitosis. It also interacts with a negative regulator of p53 and may function in a positive feedback loop with p53 that responds to cytoskeleton damage. Additionally, it can function as a co-repressor of androgen-responsive gene expression.
antibodies-online.com est synonyme de produits de recherche de haute qualité. Cherchez, trouvez et commandez des outils avec des données de validation étendues, des images, des références. Notre service clientèle scientifique est toujours à votre disposition si vous avez des questions sur la sélection ou l'application de nos produits.
Catégories LATS2 en vedette
LATS2 Anticorps
High quality antibodies with extensive validation data.
LATS2 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse, Rat
Application
ELISA, WB, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
- (1)
- (2)
N° du produit
ABIN753568
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Mouse
Application
WB, IHC (p)
Validations
- (4)
- (2)
N° du produit
ABIN1881491
Quantité
400 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse
Application
ELISA, WB, IHC (p)
Validations
- (3)
- (2)
N° du produit
ABIN545483
Quantité
400 μL
Fiche technique
Fiche technique
LATS2 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6968209
Quantité
96 tests
Fiche technique
Fiche technique
LATS2 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Insect cells (Sf21)
Validations
- (2)
N° du produit
ABIN5570074
Quantité
5 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7123724
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
N° du produit
ABIN3093544
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits LATS2
: "The polarity protein Angiomotin p130 controls dendritic spine maturation." dans: The Journal of cell biology, Vol. 217, Issue 2, pp. 715-730, (2018) (PubMed).: "Dysregulation of YAP by the Hippo pathway is involved in intervertebral disc degeneration, cell contact inhibition, and cell senescence." dans: Oncotarget, Vol. 9, Issue 2, pp. 2175-2192, (2018) (PubMed).
: "Biphasic Regulation of Yes-associated Protein (YAP) Cellular Localization, Phosphorylation, and Activity by G Protein-coupled Receptor Agonists in Intestinal Epithelial Cells: A NOVEL ROLE FOR ..." dans: The Journal of biological chemistry, Vol. 291, Issue 34, pp. 17988-8005, (2016) (PubMed).
: "LIM-domain protein AJUBA suppresses malignant mesothelioma cell proliferation via Hippo signaling cascade." dans: Oncogene, Vol. 34, Issue 1, pp. 73-83, (2015) (PubMed).
: "Inhibition of Gastric Tumor Cell Growth Using Seed-targeting LNA as Specific, Long-lasting MicroRNA Inhibitors." dans: Molecular therapy. Nucleic acids, Vol. 4, pp. e246, (2015) (PubMed).
: "Hypoxia-inducible factor 1 mediates TAZ expression and nuclear localization to induce the breast cancer stem cell phenotype." dans: Oncotarget, Vol. 5, Issue 24, pp. 12509-27, (2015) (PubMed).
: "RASSF1A-LATS1 signalling stabilizes replication forks by restricting CDK2-mediated phosphorylation of BRCA2." dans: Nature cell biology, Vol. 16, Issue 10, pp. 962-71, 1-8, (2014) (PubMed).
: "The Hippo pathway kinase Lats2 prevents DNA damage-induced apoptosis through inhibition of the tyrosine kinase c-Abl." dans: Cell death and differentiation, Vol. 20, Issue 10, pp. 1330-40, (2013) (PubMed).
: "Actin-binding and cell proliferation activities of angiomotin family members are regulated by Hippo pathway-mediated phosphorylation." dans: The Journal of biological chemistry, Vol. 288, Issue 52, pp. 37296-307, (2013) (PubMed).
: "KIBRA regulates aurora kinase activity and is required for precise chromosome alignment during mitosis." dans: The Journal of biological chemistry, Vol. 287, Issue 41, pp. 34069-77, (2012) (PubMed).
Synonymes et noms alternatifs relatifs à LATS2
large tumor suppressor kinase 2 (LATS2), large tumor suppressor 2 (Lats2), large tumor suppressor kinase 2 (Lats2), large tumor suppressor kinase 2 (lats2), 4932411G09Rik, AV277261, AW228608, KPM, lats2Protein level used designations for LATS2
- kinase phosphorylated during mitosis protein
- large tumor suppressor homolog 2
- serine/threonine-protein kinase LATS2
- serine/threonine-protein kinase kpm
- large tumor suppressor, homolog 2
- LATS (large tumor suppressor, Drosophila) homolog 2
- LATS, large tumor suppressor, homolog 2
- serine/threonine kinase KPM
- warts-like kinase
- large tumor suppressor 2-like protein
Vous êtes ici:
