LAT Produits
(Linker For Activation of T Cells (LAT))
Catégories
The protein encoded by this gene is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway. This transmembrane protein localizes to lipid rafts and acts as a docking site for SH2 domain-containing proteins. Upon phosphorylation, this protein recruits multiple adaptor proteins and downstream signaling molecules into multimolecular signaling complexes located near the site of TCR engagement. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
antibodies-online.com est synonyme de produits de recherche de haute qualité. Cherchez, trouvez et commandez des outils avec des données de validation étendues, des images, des références. Notre service clientèle scientifique est toujours à votre disposition si vous avez des questions sur la sélection ou l'application de nos produits.
Catégories LAT en vedette
LAT Anticorps
High quality antibodies with extensive validation data.
LAT Kits ELISA
Reliable ELISA kits for a wide range of species.
LAT Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
LAT recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, IHC, IF
Validations
- (7)
N° du produit
ABIN7074502
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IP, FACS
Validations
- (2)
- (5)
N° du produit
ABIN302069
Quantité
0.1 mg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC, IP, IF
Validations
- (5)
N° du produit
ABIN7127705
Quantité
100 μL
Fiche technique
Fiche technique
LAT recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6968299
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6968298
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6957484
Quantité
96 tests
Fiche technique
Fiche technique
LAT recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7123771
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1309185
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Insect Cells
Validations
- (1)
N° du produit
ABIN3082902
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits LAT
: "Endothelial-derived plasma exosome proteins in Alzheimer's disease angiopathy." dans: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 34, Issue 4, pp. 5967-5974, (2021) (PubMed).: "Rab6-dependent retrograde traffic of LAT controls immune synapse formation and T cell activation." dans: The Journal of experimental medicine, Vol. 215, Issue 4, pp. 1245-1265, (2019) (PubMed).
: "PRR7 is a transmembrane adaptor protein expressed in activated T cells involved in regulation of T cell receptor signaling and apoptosis." dans: The Journal of biological chemistry, Vol. 286, Issue 22, pp. 19617-29, (2011) (PubMed).
: "LAT and NTAL mediate immunoglobulin E-induced sustained extracellular signal-regulated kinase activation critical for mast cell survival." dans: Molecular and cellular biology, Vol. 27, Issue 12, pp. 4406-15, (2007) (PubMed).
: "Topography of signaling molecules as detected by electron microscopy on plasma membrane sheets isolated from non-adherent mast cells." dans: Journal of immunological methods, Vol. 328, Issue 1-2, pp. 139-51, (2007) (PubMed).
: "Topography of plasma membrane microdomains and its consequences for mast cell signaling." dans: European journal of immunology, Vol. 36, Issue 10, pp. 2795-806, (2006) (PubMed).
: "Transmembrane adaptor molecules: a new category of lymphoid-cell markers." dans: Blood, Vol. 107, Issue 1, pp. 213-21, (2005) (PubMed).
: "Structural basis for differential recognition of tyrosine-phosphorylated sites in the linker for activation of T cells (LAT) by the adaptor Gads." dans: The EMBO journal, Vol. 23, Issue 7, pp. 1441-51, (2004) (PubMed).
: "Negative regulation of mast cell signaling and function by the adaptor LAB/NTAL." dans: The Journal of experimental medicine, Vol. 200, Issue 8, pp. 1001-13, (2004) (PubMed).
: "Right time, right place: the organization of membrane proximal signaling." dans: Seminars in immunology, Vol. 17, Issue 1, pp. 35-49, (2004) (PubMed).
Synonymes et noms alternatifs relatifs à LAT
linker for activation of T-cells (LAT), linker for activation of T cells (lat), linker for activation of T cells (Lat), LAT, lat, LAT1, pp36Protein level used designations for LAT
- linker for activation of T cells
- 36 kDa phospho-tyrosine adapter protein
- 36 kDa phospho-tyrosine adaptor protein
- linker for activation of T cells, transmembrane adaptor
- linker for activation of T-cells family member 1
- p36-38
- pp36
- linker protein
Vous êtes ici:
