LATS2 anticorps (AA 1-100)

N° du produit ABIN7268192

Détail du produit anti-LATS2 anticorps

Antigène: LATS2 (LATS, Large Tumor Suppressor, Homolog 2 (Drosophila) (LATS2))

Épitope: AA 1-100

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LATS2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Fonction: LATS2 Rabbit pAb

Séquence: MRPKTFPATT YSGNSRQRLQ EIREGLKQPS KSSVQGLPAG PNSDTSLDAK VLGSKDATRQ QQQMRATPKF GPYQKALREI RYSLLPFANE SGTSAAAEVN

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human LATS2 (NP_055387.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur LATS2

Antigène: LATS2 (LATS, Large Tumor Suppressor, Homolog 2 (Drosophila) (LATS2))

Autre désignation: LATS2 (LATS2 Produits)

Synonymes: anticorps 4932411G09Rik, anticorps AV277261, anticorps AW228608, anticorps KPM, anticorps lats2, anticorps large tumor suppressor kinase 2, anticorps large tumor suppressor 2, anticorps LATS2, anticorps Lats2, anticorps lats2

Sujet: This gene encodes a serine/threonine protein kinase belonging to the LATS tumor suppressor family. The protein localizes to centrosomes during interphase, and early and late metaphase. It interacts with the centrosomal proteins aurora-A and ajuba and is required for accumulation of gamma-tubulin and spindle formation at the onset of mitosis. It also interacts with a negative regulator of p53 and may function in a positive feedback loop with p53 that responds to cytoskeleton damage. Additionally, it can function as a co-repressor of androgen-responsive gene expression.,LATS2,KPM,Epigenetics & Nuclear Signaling,DNA Damage & Repair,Signal Transduction,Kinase,Serine/threonine kinases,Cell Biology & Developmental Biology,Hippo Signaling Pathway,LATS2

Poids moléculaire: 120kDa

ID gène: 26524

UniProt: Q9NRM7