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EDG-2

BUD31 WB, PC Whole Cell Lysate
N° du produit ABIN924990
  • Antigène Tous les produits BUD31
    BUD31 (BUD31 Homolog (BUD31))
    Application
    Western Blotting (WB), Positive Control (PC)
    Lysate Fraction
    Whole Cell Lysate
  • Indications d'application
    For use as a positive control with EDG-2 polyclonal antibody ABIN187787 for Western blot analysis. Use 10 µl of EDG-2 cell lysate per lane as a control for using EDG-2 antibody.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Cell lysate provided in 10% glycerol, 0.063 M Tris-HCl (pH 6.8), 2% SDS and 0.002% bromophenol blue, 5% 2-mercaptoethanol.
    Stock
    -20 °C
  • Antigène
    BUD31 (BUD31 Homolog (BUD31))
    Autre désignation
    EDG-2 (BUD31 Produits)
    Synonymes
    Cwc14 Lysate, EDG-2 Lysate, EDG2 Lysate, G10 Lysate, YCR063W Lysate, fSAP17 Lysate, g10l Lysate, zgc:110615 Lysate, CWC14 Lysate, DDBDRAFT_0190998 Lysate, DDBDRAFT_0233523 Lysate, DDB_0190998 Lysate, DDB_0233523 Lysate, bud31 Lysate, Edg2 Lysate, C77604 Lysate, g10 Lysate, c77604 Lysate, BUD31 homolog Lysate, BUD31 homolog (S. cerevisiae) Lysate, protein BUD31 homolog Lysate, U2 snRNP complex subunit BUD31 Lysate, U2 snRNP complex subunit Lysate, hypothetical protein Lysate, BUD31 homolog (yeast) Lysate, BUD31 homolog L homeolog Lysate, maternal g10 transcript Lysate, Protein BUD31 homolog Lysate, BUD31 Lysate, bud31 Lysate, Bud31 Lysate, bud31.L Lysate, LOC5569643 Lysate, CC1G_08861 Lysate, bud-31 Lysate, LOC109464260 Lysate, LOC108703088 Lysate
    Sujet
    EDG-2 Transfected Cell Positive Control Lysate. Provided in 10% glycerol, 0.063 M Tris-HCl (pH 6.8), 2% SDS and 0.002% bromophenol blue, 5% 2-Mercaptoethanol. Endothelial cell differentiation gene-2 (EDG-2) receptor is a high affinity receptor for lysophosphatidic acid (LPA). EDG-2, also known as lysopholipid receptor A1, Vzg-1, mrec1.3 or GPCR26, like all other EDG receptors, couple multiple (3 or more) types of G proteins and transduce decreases in c[AMP]i through Gi and increases in [Ca 2+ ]i by augmenting phos- pholipase C through Gq/11 and beta/gamma dimmers and by induction of PI3 kinase, p125 FAK, phospholipase D by activating rho through G12/13. Human EDG-2 is present in high levels on oligodendrocytes and certain human malignant T cell lines. EDG-2 receptors (with EDG-4) may play a role in protecting cardiomyocytes from apoptosis induced by hypoxia and andrenergic stimulation.
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