Aperçu des produits pour anti-RAD1 (RAD1) Anticorps

Full name:: anti-RAD1 Homolog (S. Pombe) Anticorps (RAD1)

Chez www.anticorps-enligne.fr sont 102 RAD1 Homolog (S. Pombe) (RAD1) Anticorps de 17 de différents fournisseurs disponibles. De plus, nous expédions RAD1 Protéines (9) et beaucoup plus de produits pour cette protéine. Un total de 119 RAD1 produits sont actuellement listés.

Synonymes:: DKFZp459H1127, HRAD1, RAD1, REC1, xrad1, zgc:56502, zgc:77779

afficher tous les anticorps	Gène	GeneID	UniProt
	RAD1	5810	O60671
	RAD1	19355	Q9QWZ1
	RAD1	294800
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Pathways pertinentes pour anti-RAD1 Anticorps

M Phase

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Plus d’anticorps contre RAD1 partenaires d’interaction

Human RAD1 Homolog (S. Pombe) (RAD1) interaction partners

Dominant alleles of RAD51 (Montrer RAD51 Anticorps), TP53 (Montrer TP53 Anticorps) and XRCC1 (Montrer XRCC1 Anticorps) combined genotypes indicated a strong protective role against hereditary breast cancer.
Intramolecular binding of the rad9 (Montrer RAD9A Anticorps) C-terminus in the checkpoint clamp (Montrer PDZK1 Anticorps) Rad9 (Montrer RAD9A Anticorps)-Hus1 (Montrer HUS1 Anticorps)-Rad1 (Montrer ERCC4 Anticorps) is closely linked with its DNA binding.
Data show models for the ternary PCNA (Montrer PCNA Anticorps)/FEN1 (Montrer FEN1 Anticorps)/DNA and Rad9 (Montrer RAD9A Anticorps)-Rad1 (Montrer ERCC4 Anticorps)-Hus1 (Montrer HUS1 Anticorps) (9-1-1 complex)/FEN1 (Montrer FEN1 Anticorps)/DNA assemblies.
The RAD1 (Montrer ERCC4 Anticorps) is loaded to damaged sites where it serves as a platform for the selective recruitment of checkpoint and repair proteins.
CK2 (Montrer CSNK2A1 Anticorps) plays a crucial role in the ATR (Montrer ANTXR1 Anticorps)-dependent checkpoint pathway through its ability to phosphorylate Ser (Montrer SIGLEC1 Anticorps)-341 and Ser (Montrer SIGLEC1 Anticorps)-387 of the Rad9 (Montrer RAD9A Anticorps) subunit of the Rad9 (Montrer RAD9A Anticorps)-Hus1 (Montrer HUS1 Anticorps)-Rad1 (Montrer ERCC4 Anticorps) complex
Rad9 (Montrer RAD9A Anticorps)-Rad1 (Montrer ERCC4 Anticorps)-Hus1 (Montrer HUS1 Anticorps) complex enhances in vitro activity of 8-oxoguanine DNA glycosylase (Montrer OGG1 Anticorps).
Rad9 (Montrer RAD9A Anticorps), Hus1 (Montrer HUS1 Anticorps), and Rad1 (Montrer ERCC4 Anticorps) heterotrimeric complex chromatin binding is a proximal event in the checkpoint signaling cascade
RAD1 (Montrer ERCC4 Anticorps) is a potential intrinsic chaperone in the stabilization of HUS1 (Montrer HUS1 Anticorps) for the heterotrimeric (RAD9 (Montrer RAD9A Anticorps)-RAD1 (Montrer ERCC4 Anticorps)-HUS1 (Montrer HUS1 Anticorps)) checkpoint complex formation.
The human Rad9 (Montrer RAD9A Anticorps)/Rad1 (Montrer ERCC4 Anticorps)/Hus1 (Montrer HUS1 Anticorps) complex interacts with and stimulates DNA polymerase beta (Montrer POLB Anticorps) activity.
complex with rad9 (Montrer RAD9A Anticorps) and hus1 (Montrer HUS1 Anticorps) is a damage-specific activator of flap endonuclease 1 (Montrer FEN1 Anticorps)

Mouse (Murine) RAD1 Homolog (S. Pombe) (RAD1) interaction partners

HUS1 (Montrer HUS1 Anticorps) acts as a component of the canonical 9-1-1 complex during meiotic prophase I to promote DSB repair and further propose that RAD1 and TOPBP1 (Montrer TOPBP1 Anticorps) respond to unsynapsed chromatin through an alternative mechanism that does not require RAD9 (Montrer RAD9A Anticorps) or HUS1 (Montrer HUS1 Anticorps).
The rad1 protein is required for repairing DNA lesions induced by UV-light, HU and gamma rays, and for mediating G(2)/M and S/M checkpoint controls.
data indicate that Rad1(K185) is not a functional counterpart of PCNA (Montrer PCNA Anticorps)(K164).
data suggest that Mrad1 is important for preventing tumor development.

RAD1 profil antigène

Antigen Summary

This gene encodes a component of a heterotrimeric cell cycle checkpoint complex, known as the 9-1-1 complex, that is activated to stop cell cycle progression in response to DNA damage or incomplete DNA replication. The 9-1-1 complex is recruited by RAD17 to affected sites where it may attract specialized DNA polymerases and other DNA repair effectors. Alternatively spliced transcript variants of this gene have been described.

Alternative names and synonyms associated with RAD1

RAD1 checkpoint DNA exonuclease (RAD1) anticorps
RAD1 checkpoint DNA exonuclease (Rad1) anticorps
RAD1 homolog (S. pombe) (rad1) anticorps
RAD1 checkpoint DNA exonuclease (rad1) anticorps

DKFZp459H1127 anticorps
HRAD1 anticorps
RAD1 anticorps
REC1 anticorps
xrad1 anticorps
zgc:56502 anticorps
zgc:77779 anticorps

Protein level used designations for RAD1

DNA repair exonuclease REC1 , DNA repair exonuclease rad1 homolog , cell cycle checkpoint protein Hrad1 , cell cycle checkpoint protein RAD1 , checkpoint control protein HRAD1 , exonuclease homolog RAD1 , rad1-like DNA damage checkpoint protein , mRAD1 , RAD1 homolog (S. pombe) , RAD1 homolog , Cell cycle checkpoint protein RAD1 , cell cycle checkpoint protein rad1

GENE ID	SPECIES
5810	Homo sapiens
19355	Mus musculus
294800	Rattus norvegicus
393872	Danio rerio
427432	Gallus gallus
461928	Pan troglodytes
479366	Canis lupus familiaris
518502	Bos taurus
548799	Xenopus (Silurana) tropicalis
100173217	Pongo abelii
100528686	Ictalurus punctatus
100714852	Cavia porcellus

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