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MAP4K6 Produits

(Misshapen-Like Kinase 1 (MINK1))
This gene encodes a serine/threonine kinase belonging to the germinal center kinase (GCK) family. The protein is structurally similar to the kinases that are related to NIK and may belong to a distinct subfamily of NIK-related kinases within the GCK family. Studies of the mouse homolog indicate an up-regulation of expression in the course of postnatal mouse cerebral development and activation of the cJun N-terminal kinase (JNK) and the p38 pathways. Alternative splicing occurs at this locus and four transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Jul 2008].

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Catégories MAP4K6 en vedette

MAP4K6 Anticorps

High quality antibodies with extensive validation data.

MAP4K6 Kits ELISA

Reliable ELISA kits for a wide range of species.

MAP4K6 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

MAP4K6 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Bat, Cow, Horse, Human, Monkey, Mouse, Pig, Rat
Application IHC, IHC (p)
Validations
  • (3)
N° du produit ABIN1049061
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Bat, Hamster, Horse, Human, Monkey, Mouse, Pig, Rat
Application ELISA, IHC, IHC (p)
Validations
  • (2)
N° du produit ABIN213551
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (1)
N° du produit ABIN7187298
Quantité 100 μg
Fiche technique Fiche technique

MAP4K6 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse
Analytical Method Qualitative Cell ELISA
Validations
N° du produit ABIN5648287
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method
Validations
N° du produit ABIN1142650
Quantité 96 tests
Fiche technique Fiche technique

MAP4K6 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Insect cells (Sf21)
Validations
  • (2)
N° du produit ABIN5569450
Quantité 5 μg
Fiche technique Fiche technique
Reactivity Human
Source Insect cells (Sf9)
Validations
  • (2)
N° du produit ABIN5569601
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
N° du produit ABIN3093824
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits MAP4K6

Yu, Hu, Sheng, Fu, Wang, Chen, Pan, Zhang, Wu, Sun, Dai, Lu, Ouyang: "Dual roles of misshapen/NIK-related kinase (MINK1) in osteoarthritis subtypes through the activation of TGFβ signaling." dans: Osteoarthritis and cartilage, Vol. 28, Issue 1, pp. 112-121, (2020) (PubMed).

Fu, Xu, Qiu, Jin, Xu, Dong, Wang, Ke, Hu, Cao, Wang, Cantor, Gao, Lu: "Suppression of Th17 cell differentiation by misshapen/NIK-related kinase MINK1." dans: The Journal of experimental medicine, Vol. 214, Issue 5, pp. 1453-1469, (2017) (PubMed).

Larhammar, Huntwork-Rodriguez, Rudhard, Sengupta-Ghosh, Lewcock: "The Ste20 Family Kinases MAP4K4, MINK1, and TNIK Converge to Regulate Stress-Induced JNK Signaling in Neurons." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 37, Issue 46, pp. 11074-11084, (2017) (PubMed).

Gloerich, ten Klooster, Vliem, Koorman, Zwartkruis, Clevers, Bos: "Rap2A links intestinal cell polarity to brush border formation." dans: Nature cell biology, Vol. 14, Issue 8, pp. 793-801, (2012) (PubMed).

Strausberg, Feingold, Grouse, Derge, Klausner, Collins, Wagner, Shenmen, Schuler, Altschul, Zeeberg, Buetow, Schaefer, Bhat, Hopkins, Jordan, Moore, Max, Wang, Hsieh, Diatchenko, Marusina, Farmer et al.: "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. ..." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 26, pp. 16899-903, (2002) (PubMed).

Dan, Watanabe, Kobayashi, Yamashita-Suzuki, Fukagaya, Kajikawa, Kimura, Nakashima, Matsumoto, Ninomiya-Tsuji, Kusumi: "Molecular cloning of MINK, a novel member of mammalian GCK family kinases, which is up-regulated during postnatal mouse cerebral development." dans: FEBS letters, Vol. 469, Issue 1, pp. 19-23, (2000) (PubMed).

Synonymes et noms alternatifs relatifs à MAP4K6

misshapen like kinase 1 (MINK1), misshapen-like kinase 1 (Mink1), misshapen-like kinase 1 (zebrafish) (Mink1), B55, hMINK, hMINKbeta, MAP4K6, Map4k6, MEKKK 6, MINK, MINK1, RP23-122P1.6, YSK2, Ysk2, ZC3

Protein level used designations for MAP4K6

  • misshapen-like kinase 1 (zebrafish)
  • misshapen/NIK-related kinase
  • GCK family kinase MINK
  • MAPK/ERK kinase kinase kinase 6
  • MEK kinase kinase 6
  • MEKKK 6
  • mitogen-activated protein kinase kinase kinase kinase 6
  • serine/threonine protein kinase
  • GCK family kinase MiNK
  • GCK family kinase
  • Misshapen/NIKs-related kinase
  • Yeast Sps1/Ste20-related kinase 2
  • misshapen-like kinase 1
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