MCM10 Produits
(Minichromosome Maintenance Deficient 10 (MCM10))
Catégories
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre-RC) and it may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein can interact with MCM2 and MCM6, as well as with the origin recognition protein ORC2. It is regulated by proteolysis and phosphorylation in a cell cycle-dependent manner. Studies of a similar protein in Xenopus suggest that the chromatin binding of this protein at the onset of DNA replication is after pre-RC assembly and before origin unwinding. Alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Jul 2008].
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Catégories MCM10 en vedette
MCM10 Anticorps
High quality antibodies with extensive validation data.
MCM10 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
MCM10 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, IHC
Validations
- (3)
N° du produit
ABIN6263157
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IF
Validations
- (2)
N° du produit
ABIN949450
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human, Mouse
Application
IF
Validations
- (1)
N° du produit
ABIN7261385
Quantité
200 μL
Fiche technique
Fiche technique
MCM10 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6211737
Quantité
96 tests
Fiche technique
Fiche technique
MCM10 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1310546
Quantité
25 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
N° du produit
ABIN3093779
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
N° du produit
ABIN3134892
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits MCM10
: "Singlet Oxygen-Mediated Oxidation during UVA Radiation Alters the Dynamic of Genomic DNA Replication." dans: PLoS ONE, Vol. 10, Issue 10, pp. e0140645, (2015) (PubMed).: "Efficient expression and purification of human replication fork-stabilizing factor, Claspin, from mammalian cells: DNA-binding activity and novel protein interactions." dans: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 16, Issue 8, pp. 842-56, (2011) (PubMed).
: "Human Mcm10 regulates the catalytic subunit of DNA polymerase-alpha and prevents DNA damage during replication." dans: Molecular biology of the cell, Vol. 18, Issue 10, pp. 4085-95, (2007) (PubMed).
: "The Chk1-mediated S-phase checkpoint targets initiation factor Cdc45 via a Cdc25A/Cdk2-independent mechanism." dans: The Journal of biological chemistry, Vol. 281, Issue 41, pp. 30631-44, (2006) (PubMed).
Synonymes et noms alternatifs relatifs à MCM10
Minichromosome maintenance 10 (Mcm10), minichromosome maintenance 10 replication initiation factor (MCM10), minichromosome maintenance 10 replication initiation factor (Mcm10), minichromosome maintenance 10 replication initiation factor L homeolog (mcm10.L), 2410041F14Rik, AU018508, C79164, C330019M07Rik, CG9241, CNA43, Dmel\\CG9241, DmMCM10, DNA43, mcm10, Scim19, xmcm10Protein level used designations for MCM10
- CG9241-PA
- Mcm10-PA
- sensitized chromosome inheritance modifier 19
- MCM10 minichromosome maintenance deficient 10
- homolog of yeast MCM10
- hsMCM10
- protein MCM10 homolog
- minichromosome maintenance deficient 10
- Mcm10p
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