MCC Produits
(Mutated in Colorectal Cancers (MCC))
Catégories
This gene is a candidate colorectal tumor suppressor gene that is thought to negatively regulate cell cycle progression. The orthologous gene in the mouse expresses a phosphoprotein associated with the plasma membrane and membrane organelles, and overexpression of the mouse protein inhibits entry into S phase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Catégories MCC en vedette
MCC Anticorps
High quality antibodies with extensive validation data.
MCC Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
MCC recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IP
Validations
- (4)
N° du produit
ABIN950122
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, RNAi
Validations
- (4)
N° du produit
ABIN561756
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
ELISA, IHC, IF
Validations
- (3)
N° du produit
ABIN7148294
Quantité
100 μg
Fiche technique
Fiche technique
MCC recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1310523
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1310525
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
N° du produit
ABIN3091956
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits MCC
: "'Default' generated neonatal regulatory T cells are hypomethylated at conserved non-coding sequence 2 and promote long-term cardiac allograft survival." dans: Immunology, Vol. 143, Issue 4, pp. 618-30, (2014) (PubMed).: "CCL21 mediates CD4+ T-cell costimulation via a DOCK2/Rac-dependent pathway." dans: Blood, Vol. 114, Issue 3, pp. 580-8, (2009) (PubMed).
: "Loss of heterozygosity of APC and MCC genes in oral squamous cell carcinomas in Taiwan." dans: Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, Vol. 26, Issue 7, pp. 322-6, (1997) (PubMed).
: "MCC, a cytoplasmic protein that blocks cell cycle progression from the G0/G1 to S phase." dans: The Journal of biological chemistry, Vol. 271, Issue 17, pp. 10341-6, (1996) (PubMed).
: "Abnormalities affecting the APC and MCC tumour suppressor gene loci on chromosome 5q occur frequently in gastric cancer but not in pancreatic cancer." dans: International journal of cancer. Journal international du cancer, Vol. 55, Issue 4, pp. 598-603, (1993) (PubMed).
: "MCC, a candidate familial polyposis gene in 5q.21, shows frequent allele loss in colorectal and lung cancer." dans: Oncogene, Vol. 6, Issue 10, pp. 1881-6, (1991) (PubMed).
: "Identification of a gene located at chromosome 5q21 that is mutated in colorectal cancers." dans: Science (New York, N.Y.), Vol. 251, Issue 4999, pp. 1366-70, (1991) (PubMed).
Synonymes et noms alternatifs relatifs à MCC
mutated in colorectal cancers (MCC), mutated in colorectal cancers (mcc), mutated in colorectal cancers (Mcc), D18Ertd451e, E330037C19, MCC, mcc1, MCC1, RGD1561988Protein level used designations for MCC
- mutated in colorectal cancers
- colorectal mutant cancer protein
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