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NKX6-1 Produits

(NK6 Homeobox 1 (NKX6-1))
In the pancreas, NKX6.1 is required for the development of beta cells and is a potent bifunctional transcription regulator that binds to AT-rich sequences within the promoter region of target genes Iype et al. (2004) [PubMed 15056733].[supplied by OMIM, Mar 2008].

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Catégories NKX6-1 en vedette

NKX6-1 Anticorps

High quality antibodies with extensive validation data.

NKX6-1 Kits ELISA

Reliable ELISA kits for a wide range of species.

NKX6-1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

NKX6-1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application IHC, StM
Validations
  • (4)
N° du produit ABIN6940213
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, ICC, IP
Validations
  • (2)
N° du produit ABIN7436357
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA
Validations
  • (2)
N° du produit ABIN518370
Quantité 100 μg
Fiche technique Fiche technique

NKX6-1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6958207
Quantité 96 tests
Fiche technique Fiche technique

NKX6-1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
N° du produit ABIN3084441
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
N° du produit ABIN3128039
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7399076
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits NKX6-1

Griffiths, Crick, Meljon, Theofilopoulos, Abdel-Khalik, Yutuc, Parker, Kelly, Kelly, Arenas, Wang: "Additional pathways of sterol metabolism: Evidence from analysis of Cyp27a1-/- mouse brain and plasma." dans: Biochimica et biophysica acta. Molecular and cell biology of lipids, Vol. 1864, Issue 2, pp. 191-211, (2019) (PubMed).

Wilson, Spaeth, Karp, Stocks, Hoopes, Stein, Moore: "B lymphocytes protect islet β cells in diabetes prone NOD mice treated with imatinib." dans: JCI insight, Vol. 5, (2019) (PubMed).

Wang, Sterr, Ansarullah, Burtscher, Böttcher, Beckenbauer, Siehler, Meitinger, Häring, Staiger, Cernilogar, Schotta, Irmler, Beckers, Wright, Bakhti, Lickert: "Point mutations in the PDX1 transactivation domain impair human β-cell development and function." dans: Molecular metabolism, Vol. 24, pp. 80-97, (2019) (PubMed).

Spaeth, Liu, Peters, Guo, Osipovich, Mohammadi, Roy, Bhushan, Magnuson, Hebrok, Wright, Stein: "The Pdx1 Bound Swi/Snf Chromatin Remodeling Complex Regulates Pancreatic Progenitor Cell Proliferation and Mature Islet β Cell Function." dans: Diabetes, (2019) (PubMed).

Vethe, Ghila, Berle, Hoareau, Haaland, Scholz, Paulo, Chera, Ræder: "The Effect of Wnt Pathway Modulators on Human iPSC-Derived Pancreatic Beta Cell Maturation." dans: Frontiers in endocrinology, Vol. 10, pp. 293, (2019) (PubMed).

Wang, Malinowski, Beckenbauer, Siehler, Blöchinger, Meitinger, Häring, Staiger, Burtscher, Lickert: "Generation of a human induced pluripotent stem cell line (HMGUi002-A) from a healthy male individual." dans: Stem cell research, Vol. 39, pp. 101531, (2019) (PubMed).

Mohan, Radha, Nguyen, Stawiski, Pahuja, Goldstein, Tom, Anjana, Kong-Beltran, Bhangale, Jahnavi, Chandni, Gayathri, George, Zhang, Murugan, Phalke, Chaudhuri, Gupta, Zhang, Santhosh, Stinson et al.: "Comprehensive genomic analysis identifies pathogenic variants in maturity-onset diabetes of the young (MODY) patients in South India. ..." dans: BMC medical genetics, Vol. 19, Issue 1, pp. 22, (2018) (PubMed).

Spaeth, Gupte, Perelis, Yang, Cyphert, Guo, Liu, Guo, Bass, Magnuson, Wright, Stein: "Defining a Novel Role for the PDX1 Transcription Factor in Islet β Cell Maturation and Proliferation During Weaning." dans: Diabetes, (2017) (PubMed).

Bader, Migliorini, Gegg, Moruzzi, Gerdes, Roscioni, Bakhti, Brandl, Irmler, Beckers, Aichler, Feuchtinger, Leitzinger, Zischka, Wang-Sattler, Jastroch, Tschöp, Machicao, Staiger, Häring, Chmelova et al.: "Identification of proliferative and mature β-cells in the islets of Langerhans. ..." dans: Nature, Vol. 535, Issue 7612, pp. 430-4, (2016) (PubMed).

Theofilopoulos, Griffiths, Crick, Yang, Meljon, Ogundare, Kitambi, Lockhart, Tuschl, Clayton, Morris, Martinez, Reddy, Martinuzzi, Bassi, Honda, Mizuochi, Kimura, Nittono, De Michele, Carbone et al.: "Cholestenoic acids regulate motor neuron survival via liver X receptors. ..." dans: The Journal of clinical investigation, Vol. 124, Issue 11, pp. 4829-42, (2014) (PubMed).

Synonymes et noms alternatifs relatifs à NKX6-1

NK6 homeobox 1 (nkx6-1), NK6 homeobox 1 (NKX6-1), NK6 homeobox 1 (nkx6.1), NK6 homeobox 1 L homeolog (nkx6-1.L), NK6 homeobox 1 (Nkx6-1), nkx6.1, NKX6.1, Nkx6.1, nkx6a, NKX6A, Nkx6a, Nkx61, zgc:92879

Protein level used designations for NKX6-1

  • NK6 transcription factor related, locus 1
  • NK6 homeobox 1
  • NK homeo box, family 6, member A
  • NK homeobox, family 6, A
  • NK6 transcription factor homolog A
  • homeobox protein NK-6 homolog A
  • homeobox protein Nkx-6.1
  • NK6 transcription factor related locus 1
  • Drosophila NK transcription factor related, gene family 6, locus 1
  • homeodomain transcription factor Nkx6.1
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