NLRP1 Produits
(NLR Family, Pyrin Domain Containing 1 (NLRP1))
Catégories
This gene encodes a member of the Ced-4 family of apoptosis proteins. Ced-family members contain a caspase recruitment domain (CARD) and are known to be key mediators of programmed cell death. The encoded protein contains a distinct N-terminal pyrin-like motif, which is possibly involved in protein-protein interactions. This protein interacts strongly with caspase 2 and weakly with caspase 9. Overexpression of this gene was demonstrated to induce apoptosis in cells. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008].
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Catégories NLRP1 en vedette
NLRP1 Anticorps
High quality antibodies with extensive validation data.
NLRP1 Kits ELISA
Reliable ELISA kits for a wide range of species.
NLRP1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC, IF
Validations
- (7)
N° du produit
ABIN7268935
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC, IF
Validations
- (3)
N° du produit
ABIN7160821
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Cow, Dog, Horse, Human, Monkey, Mouse
Application
WB, IHC, IHC (p)
Validations
- (2)
N° du produit
ABIN768983
Quantité
50 μg
Fiche technique
Fiche technique
NLRP1 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6968954
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6974912
Quantité
96 tests
Fiche technique
Fiche technique
NLRP1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
N° du produit
ABIN3094175
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
N° du produit
ABIN2713167
Quantité
20 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits NLRP1
: "Reduction of SIRT1 epigenetically upregulates NALP1 expression and contributes to neuropathic pain induced by chemotherapeutic drug bortezomib." dans: Journal of neuroinflammation, Vol. 15, Issue 1, pp. 292, (2019) (PubMed).: "Inflammasome Activation Induces Pyroptosis in the Retina Exposed to Ocular Hypertension Injury." dans: Frontiers in molecular neuroscience, Vol. 12, pp. 36, (2019) (PubMed).
: "Schwann cell transplantation exerts neuroprotective roles in rat model of spinal cord injury by combating inflammasome activation and improving motor recovery and remyelination." dans: Metabolic brain disease, (2019) (PubMed).
: "Low-level light emitting diode (LED) therapy suppresses inflammasome-mediated brain damage in experimental ischemic stroke." dans: Journal of biophotonics, (2017) (PubMed).
: "NLRP1 inflammasome is activated in patients with medial temporal lobe epilepsy and contributes to neuronal pyroptosis in amygdala kindling-induced rat model." dans: Journal of neuroinflammation, Vol. 12, pp. 18, (2015) (PubMed).
: "Intermittent fasting attenuates inflammasome activity in ischemic stroke." dans: Experimental neurology, Vol. 257, pp. 114-9, (2014) (PubMed).
: "Intravenous immunoglobulin suppresses NLRP1 and NLRP3 inflammasome-mediated neuronal death in ischemic stroke." dans: Cell death & disease, Vol. 4, pp. e790, (2013) (PubMed).
: "NLRP1 haplotypes associated with vitiligo and autoimmunity increase interleukin-1? processing via the NLRP1 inflammasome." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 8, pp. 2952-6, (2013) (PubMed).
: "Mite allergen is a danger signal for the skin via activation of inflammasome in keratinocytes." dans: The Journal of allergy and clinical immunology, Vol. 127, Issue 3, pp. 806-14.e1-4, (2011) (PubMed).
: "Inflammasome mRNA expression in human monocytes during early septic shock." dans: American journal of respiratory and critical care medicine, Vol. 177, Issue 9, pp. 983-8, (2008) (PubMed).
Synonymes et noms alternatifs relatifs à NLRP1
NLR family pyrin domain containing 1 (NLRP1), NLR family pyrin domain containing 1 (Nlrp1), CARD7, CIDED, CLR17.1, DEFCAP, DEFCAP-L/S, NAC, NALP1, PP1044, SLEV1, VAMAS1Protein level used designations for NLRP1
- NACHT, LRR and PYD containing protein 1
- NACHT, LRR and PYD domains-containing protein 1
- NACHT, leucine rich repeat and PYD (pyrin domain) containing 1
- NACHT, leucine rich repeat and PYD containing 1
- caspase recruitment domain protein 7
- caspase recruitment domain-containing protein 7
- death effector filament-forming Ced-4-like apoptosis protein
- nucleotide-binding domain and caspase recruitment domain
- nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 1
- NLR family, pyrin domain containing 1
- NLR family pyrin domain containing 1
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