Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

NLRC4 Produits

(NLR Family, CARD Domain Containing 4 (NLRC4))
In C. elegans, Ced4 binds and activates Ced3, an apoptotic initiator caspase, via caspase-associated recruitment domains (CARDs). Human Ced4 homologs include APAF1 (MIM 602233), NOD1/CARD4 (MIM 605980), and NOD2/CARD15 (MIM 605956). These proteins have at least 1 N-terminal CARD domain followed by a centrally located nucleotide-binding domain (NBD or NACHT) and a C-terminal regulatory domain, found only in mammals, that contains either WD40 repeats or leucine-rich repeats (LRRs). CARD12 is a member of the Ced4 family and can induce apoptosis.[supplied by OMIM, Mar 2008].

antibodies-online.com est synonyme de produits de recherche de haute qualité. Cherchez, trouvez et commandez des outils avec des données de validation étendues, des images, des références. Notre service clientèle scientifique est toujours à votre disposition si vous avez des questions sur la sélection ou l'application de nos produits.

Catégories NLRC4 en vedette

NLRC4 Anticorps

High quality antibodies with extensive validation data.

NLRC4 Kits ELISA

Reliable ELISA kits for a wide range of species.

NLRC4 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

NLRC4 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse
Application IHC, IF
Validations
  • (5)
N° du produit ABIN7008065
Quantité 60 μL
Fiche technique Fiche technique
Reactivity Human, Mouse
Application WB, IHC, ELISA, ICC, FACS
Validations
  • (4)
N° du produit ABIN5611209
Quantité 0.1 mg
Fiche technique Fiche technique
Reactivity Human
Application WB, IF
Validations
  • (4)
N° du produit ABIN6144657
Quantité 100 μL
Fiche technique Fiche technique

NLRC4 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6968953
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6962707
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6958209
Quantité 96 tests
Fiche technique Fiche technique

NLRC4 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7124183
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1312662
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
N° du produit ABIN3094174
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits NLRC4

Jabir, Sulaiman, Taqi, Li: "Iraqi propolis increases degradation of IL-1β and NLRC4 by autophagy following Pseudomonas aeruginosa infection." dans: Microbes and infection, Vol. 20, Issue 2, pp. 89-100, (2018) (PubMed).

Cividini, Tozzi, Galli, Pesi, Camici, Dumontet, Jordheim, Allegrini: "Cytosolic 5'-nucleotidase II interacts with the leucin rich repeat of NLR family member Ipaf." dans: PLoS ONE, Vol. 10, Issue 3, pp. e0121525, (2015) (PubMed).

Hughes, Vivar, Kennis, Pratt-Thomas, Lowe, Shaner, Nietert, Spruill, Purves: "Inflammasomes are important mediators of cyclophosphamide-induced bladder inflammation." dans: American journal of physiology. Renal physiology, Vol. 306, Issue 3, pp. F299-308, (2014) (PubMed).

Akhter, Caution, Abu Khweek, Tazi, Abdulrahman, Abdelaziz, Voss, Doseff, Hassan, Azad, Schlesinger, Wewers, Gavrilin, Amer: "Caspase-11 promotes the fusion of phagosomes harboring pathogenic bacteria with lysosomes by modulating actin polymerization." dans: Immunity, Vol. 37, Issue 1, pp. 35-47, (2012) (PubMed).

Larisch, Yi, Lotan, Kerner, Eimerl, Tony Parks, Gottfried, Birkey Reffey, de Caestecker, Danielpour, Book-Melamed, Timberg, Duckett, Lechleider, Steller, Orly, Kim, Roberts: "A novel mitochondrial septin-like protein, ARTS, mediates apoptosis dependent on its P-loop motif." dans: Nature cell biology, Vol. 2, Issue 12, pp. 915-21, (2001) (PubMed).

Zieger, Tran, Hainmann, Wunderle, Zgaga-Griesz, Blaser, Ware: "Characterization and expression analysis of two human septin genes, PNUTL1 and PNUTL2." dans: Gene, Vol. 261, Issue 2, pp. 197-203, (2001) (PubMed).

Poyet, Srinivasula, Tnani, Razmara, Fernandes-Alnemri, Alnemri: "Identification of Ipaf, a human caspase-1-activating protein related to Apaf-1." dans: The Journal of biological chemistry, Vol. 276, Issue 30, pp. 28309-13, (2001) (PubMed).

Geddes, Wang, Huang, Lavellee, Manji, Brown, Jurman, Cao, Morgenstern, Merriam, Glucksmann, DiStefano, Bertin: "Human CARD12 is a novel CED4/Apaf-1 family member that induces apoptosis." dans: Biochemical and biophysical research communications, Vol. 284, Issue 1, pp. 77-82, (2001) (PubMed).

Puthalakath, Villunger, OReilly, Beaumont, Coultas, Cheney, Huang, Strasser: "Bmf: a proapoptotic BH3-only protein regulated by interaction with the myosin V actin motor complex, activated by anoikis." dans: Science (New York, N.Y.), Vol. 293, Issue 5536, pp. 1829-32, (2001) (PubMed).

Hunt, Evan: "Apoptosis. Till death us do part." dans: Science (New York, N.Y.), Vol. 293, Issue 5536, pp. 1784-5, (2001) (PubMed).

Synonymes et noms alternatifs relatifs à NLRC4

NLR family CARD domain containing 4 (NLRC4), NLR family, CARD domain containing 4 (Nlrc4), 9530011P19Rik, CARD12, Card12, CLAN, CLAN1, CLANA, CLANB, CLANC, CLAND, CLR2.1, IPAF

Protein level used designations for NLRC4

  • caspase recruitment domain protein 12
  • NLR family CARD domain-containing protein 4
  • ice protease-activating factor
  • ipaf
  • NLR family, CARD domain containing 4
  • CARD, LRR, and NACHT-containing protein
  • ICE-protease activating factor
  • NOD-like receptor C4
  • caspase recruitment domain family, member 12
  • caspase recruitment domain-containing protein 12
  • nucleotide-binding oligomerization domain, leucine rich repeat and CARD domain containing 4
Vous êtes ici:
Support technique