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anti-Human Retinoic Acid Receptor alpha Anticorps:
anti-Mouse (Murine) Retinoic Acid Receptor alpha Anticorps:
anti-Rat (Rattus) Retinoic Acid Receptor alpha Anticorps:
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Human Monoclonal Retinoic Acid Receptor alpha Primary Antibody pour EMSA, ICC - ABIN2668711
Reichrath, Mittmann, Kamradt, Müller: Expression of retinoid-X receptors (-alpha,-beta,-gamma) and retinoic acid receptors (-alpha,-beta,-gamma) in normal human skin: an immunohistological evaluation. dans The Histochemical journal 1997
Show all 2 Pubmed References
Human Monoclonal Retinoic Acid Receptor alpha Primary Antibody pour IHC (p), ELISA - ABIN519635
Voss, Collin, Dixon, Thomas: Moz and retinoic acid coordinately regulate H3K9 acetylation, Hox gene expression, and segment identity. dans Developmental cell 2009
Human Polyclonal Retinoic Acid Receptor alpha Primary Antibody pour IHC (p), IHC - ABIN268790
Farias, Ong, Ghyselinck, Nakajo, Kuppumbatti, Mira y Lopez: Cellular retinol-binding protein I, a regulator of breast epithelial retinoic acid receptor activity, cell differentiation, and tumorigenicity. dans Journal of the National Cancer Institute 2005
Human Monoclonal Retinoic Acid Receptor alpha Primary Antibody pour IHC (fro), WB - ABIN152363
Choi, Park, Sockanathan: Activated retinoid receptors are required for the migration and fate maintenance of subsets of cortical neurons. dans Development (Cambridge, England) 2014
Our findings unveil a novel essential oncogenic activity of PML (Montrer PML Anticorps)/RARA in Acute promyelocitic leukemia
Findings reveal a previously unrecognized role of c-Myc (Montrer MYC Anticorps) as a potential ceRNA for PML (Montrer PML Anticorps)/RARalpha in acute promyelocytic leukemia (Montrer PML Anticorps).
RARalpha regulates Arp2/3-mediated actin cytoskeletal dynamics through a non-genomic signaling pathway
It has been shown that the AP-1 (Montrer FOSB Anticorps) family member JunB (Montrer JUNB Anticorps) and retinoic acid receptor alpha (RARa) mediate catalase (Montrer CAT Anticorps) transcriptional activation and repression, respectively, by controlling chromatin remodeling through a histone deacetylases-dependent mechanism.
Work identifies the TP53 (Montrer TP53 Anticorps) tumor suppressor as a novel target through which NPM1 (Montrer NPM1 Anticorps)-RARA impacts leukemogenesis.
Dual small interfering RNA (siRNA) silencing of RARalpha and RARgamma reversed RA blockade of P4-induced CK5 (Montrer KRT5 Anticorps). Using promoter deletion analysis, we identified a region 1.1 kb upstream of the CK5 (Montrer KRT5 Anticorps) transcriptional start site that is necessary for P4 activation and contains a putative progesterone response element (PRE
High RARA expression is associated with acute myeloid leukemia (Montrer BCL11A Anticorps).
Data suggest that the binding of Z-10 to RXRalpha (Montrer RXRA Anticorps) inhibited the interaction of RXRalpha (Montrer RXRA Anticorps) with PML (Montrer PML Anticorps)-RARalpha, leading to Z-10's selective induction of PML (Montrer PML Anticorps)-RARalpha degradation.
PML (Montrer PML Anticorps)-RARa bcr1 (Montrer BCR Anticorps) fusion is not responsible for colorectal tumor development.
overexpression of NLS (Montrer ALDH1A2 Anticorps)-RARalpha promoted the proliferation of APL (Montrer FASL Anticorps) cells and inhibited their differentiation via the PI3K (Montrer PIK3CA Anticorps)/AKT (Montrer AKT1 Anticorps) signaling pathway.
RARalpha competes with other PFN2a-binding proteins bearing PRMs and involved in actin filaments elongation. Consequently, the actin filament network is altered and MEFs adhesion is decreased. This novel role opens novel avenues for the understanding of pathologies characterized by increased levels of cytoplasmic RARalpha.
These data suggest that impairment of cardiac RARalpha signaling may be a novel mechanism that is directly linked to pathological stimuli-induced diastolic dysfunction.
Retinoic acid receptor alpha agonist all trans retinoic acid can protect the liver from ischemia reperfusion injury by promoting autophagy, which is dependent on Foxo3 (Montrer FOXO3 Anticorps)/p-Akt (Montrer AKT1 Anticorps)/Foxo1 (Montrer FOXO1 Anticorps) signaling.
both the PML (Montrer PML Anticorps)-RARA-driven competitive transplantation advantage and development of acute promyelocytic leukemia (Montrer PML Anticorps) (APL (Montrer FASL Anticorps)) required DNMT3A (Montrer DNMT3A Anticorps)
the reprogramming of epiblast stem cells into embryonic stem cell-like cells also requires low levels of retinoic acid (RA), which can modulate Wnt (Montrer WNT2 Anticorps) signalling through physical interactions of RARs (Montrer RARS Anticorps) with beta-catenin (Montrer CTNNB1 Anticorps).
our findings challenge the predominant model in the field and we propose that PML (Montrer PML Anticorps)/RARA initiates leukemia by subtly shifting cell fate decisions within the promyelocyte compartment.
DNA-binding-defective PML (Montrer PML Anticorps)/RARA mutants could not repress the transcription of retinoic acid regulated genes.
although X-RARA fusion proteins have been suggested to act by blocking retinoid-dependent transcriptional programs , we observed a surprising paucity of natural retinoids capable of transactivating Gal4 (Montrer LGALS4 Anticorps)-RARA in primary mouse bone marrow cells
The results indicate a physiological role for RARgamma as a negative regulator of osteoclastogenesis in vivo and in vitro, and reveal distinct influences of RARalpha and RARgamma in bone structure regulation.
Data suggest that retinoic acid and GM-CSF (Montrer CSF2 Anticorps)-induced retinal dehydrogenase 2 (RALDH2 (Montrer ALDH1A2 Anticorps)) expression in dendritic cells requires cooperative binding of transcription factor Sp1 (Montrer SP1 Anticorps) via the RA receptor/retinoid X receptor (Montrer RXRB Anticorps) complex to the Aldh1a2 (Montrer ALDH1A1 Anticorps) promoter.
Increased expression of mammary TRbeta1 (Montrer THRB Anticorps) and DIO2 (Montrer DIO2 Anticorps), and decreased RXRalpha (Montrer RXRA Anticorps), provide a mechanism to increase thyroid hormone (Montrer PTH Anticorps) activity within the mammary gland during lactation.
results show role for retinoic acid receptor (Montrer RARB Anticorps) as a regulator of spatial patterning of the pre-placodal ectoderm (PPE)through Tbx1 and RIPPLY3; demonstrate that Ripply3, acting downstream of RAR (Montrer RAB40B Anticorps) signaling, is key player in establishing boundaries in the PPE
This gene represents a nuclear retinoic acid receptor. The encoded protein, retinoic acid receptor alpha, regulates transcription in a ligand-dependent manner. This gene has been implicated in regulation of development, differentiation, apoptosis, granulopoeisis, and transcription of clock genes. Translocations between this locus and several other loci have been associated with acute promyelocytic leukemia. Alternatively spliced transcript variants have been found for this locus.
retinoic acid receptor alpha
, retinoic acid receptor, alpha
, retinoic acid receptor alpha-like
, nuclear receptor subfamily 1 group B member 1
, nucleophosmin-retinoic acid receptor alpha fusion protein NPM-RAR long form
, retinoic acid nuclear receptor alpha variant 1
, retinoic acid nuclear receptor alpha variant 2
, retinoic acid receptor, alpha polypeptide
, RAR alpha 1
, rar alpha
, xRAR alpha
, retinoic acid receptor alpha 1 isoform