PAK1 Produits
(P21-Activated Kinase 1 (PAK1))
Catégories
This gene encodes a family member of serine/threonine p21-activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2010].
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Catégories PAK1 en vedette
PAK1 Anticorps
High quality antibodies with extensive validation data.
PAK1 Kits ELISA
Reliable ELISA kits for a wide range of species.
PAK1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
PAK1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, IF, IHC (p), ICC
Validations
- (1)
- (6)
N° du produit
ABIN2855705
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IF, IHC (p), IP
Validations
- (1)
- (7)
N° du produit
ABIN562102
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (5)
N° du produit
ABIN7442222
Quantité
100 μL
Fiche technique
Fiche technique
PAK1 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validations
N° du produit
ABIN1380784
Quantité
2 x 96 tests
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validations
N° du produit
ABIN1380245
Quantité
2 x 96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN5593908
Quantité
96 tests
Fiche technique
Fiche technique
PAK1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Insect cells (Sf21)
Validations
- (2)
N° du produit
ABIN5570583
Quantité
5 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (2)
N° du produit
ABIN5569917
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Insect cells (Sf9)
Validations
- (2)
N° du produit
ABIN5570582
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits PAK1
: "The metastatic promoter DEPDC1B induces epithelial-mesenchymal transition and promotes prostate cancer cell proliferation via Rac1-PAK1 signaling." dans: Clinical and translational medicine, Vol. 10, Issue 6, pp. e191, (2020) (PubMed).: "Effect of Th9/IL-9 on the growth of gastric cancer in nude mice." dans: OncoTargets and therapy, Vol. 12, pp. 2225-2234, (2019) (PubMed).
: "p21-activated kinase 1 activity is required for histone H3 Ser10 phosphorylation and chromatin condensation in mouse oocyte meiosis." dans: Reproduction, fertility, and development, Vol. 29, Issue 7, pp. 1287-1296, (2018) (PubMed).
: "Uterine RAC1 via Pak1-ERM signaling directs normal luminal epithelial integrity conducive to on-time embryo implantation in mice." dans: Cell death and differentiation, Vol. 23, Issue 1, pp. 169-81, (2016) (PubMed).
: "Thymoquinone-induced conformational changes of PAK1 interrupt prosurvival MEK-ERK signaling in colorectal cancer." dans: Molecular cancer, Vol. 13, pp. 201, (2014) (PubMed).
: "Regulation of Stat5 by FAK and PAK1 in Oncogenic FLT3- and KIT-Driven Leukemogenesis." dans: Cell reports, Vol. 9, Issue 4, pp. 1333-48, (2014) (PubMed).
: "SAD-A potentiates glucose-stimulated insulin secretion as a mediator of glucagon-like peptide 1 response in pancreatic ? cells." dans: Molecular and cellular biology, Vol. 33, Issue 13, pp. 2527-34, (2013) (PubMed).
: "Phosphorylation of histone H3 on Ser10 by auto-phosphorylated PAK1 is not essential for chromatin condensation and meiotic progression in porcine oocytes." dans: Journal of animal science and biotechnology, Vol. 4, Issue 1, pp. 13, (2013) (PubMed).
: "Initial quantitative proteomic map of 28 mouse tissues using the SILAC mouse." dans: Molecular & cellular proteomics : MCP, Vol. 12, Issue 6, pp. 1709-22, (2013) (PubMed).
: "P21 activated kinase-1 (Pak1) promotes prostate tumor growth and microinvasion via inhibition of transforming growth factor β expression and enhanced matrix metalloproteinase 9 secretion." dans: The Journal of biological chemistry, Vol. 288, Issue 5, pp. 3025-35, (2013) (PubMed).
Synonymes et noms alternatifs relatifs à PAK1
p21 protein (Cdc42/Rac)-activated kinase 1 S homeolog (pak1.S), p21 (RAC1) activated kinase 1 (PAK1), p21 protein (Cdc42/Rac)-activated kinase 1 (Pak1), p21 (RAC1) activated kinase 1 (Pak1), Serine/threonine-protein kinase pak-1 (pak-1), AW045634, pak, pak-1, PAK-1, Paka, pakalpha, PAKalpha, X-PAK1, XPak1Protein level used designations for PAK1
- p21 GTPase-associated kinase 1
- p21-activated kinase 1
- p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast)
- putative CDKN1A-activated kinase 1
- STE20 homolog, yeast
- alpha-PAK
- p21/Cdc42/Rac1-activated kinase 1 (yeast Ste20-related)
- p65-PAK
- serine/threonine-protein kinase PAK 1
- CDC42/RAC effector kinase PAK-A
- activated protein kinase alpha
- PAK-1
- p21 (CDKN1A)-activated kinase 1
- p68-PAK
- protein kinase MUK2
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