PAK4 Produits
(P21-Activated Kinase 4 (PAK4))
Catégories
PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3 and PAK4. PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. They serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK4 interacts specifically with the GTP-bound form of Cdc42Hs and weakly activates the JNK family of MAP kinases. PAK4 is a mediator of filopodia formation and may play a role in the reorganization of the actin cytoskeleton. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Catégories PAK4 en vedette
PAK4 Anticorps
High quality antibodies with extensive validation data.
PAK4 Kits ELISA
Reliable ELISA kits for a wide range of species.
PAK4 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
PAK4 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (4)
N° du produit
ABIN7439984
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC, IF
Validations
- (4)
N° du produit
ABIN7169132
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human, Mouse
Application
WB, ELISA, FACS
Validations
- (5)
N° du produit
ABIN3032118
Quantité
0.4 mL
Fiche technique
Fiche technique
PAK4 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6958368
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN5564605
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN1571715
Quantité
96 tests
Fiche technique
Fiche technique
PAK4 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Insect cells (Sf21)
Validations
- (2)
N° du produit
ABIN5569703
Quantité
5 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (2)
N° du produit
ABIN5569960
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Insect cells (Sf9)
Validations
- (2)
N° du produit
ABIN5570591
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits PAK4
: "p21-Activated Kinase 4 Signaling Promotes Japanese Encephalitis Virus-Mediated Inflammation in Astrocytes." dans: Frontiers in cellular and infection microbiology, Vol. 7, pp. 271, (2018) (PubMed).: "Adenovirus Modulates Toll-Like Receptor 4 Signaling by Reprogramming ORP1L-VAP Protein Contacts for Cholesterol Transport from Endosomes to the Endoplasmic Reticulum." dans: Journal of virology, Vol. 91, Issue 6, (2017) (PubMed).
: "p21-Activated kinase 4 predicts early recurrence and poor survival in patients with nonmetastatic clear cell renal cell carcinoma." dans: Urologic oncology, Vol. 33, Issue 5, pp. 205.e13-21, (2015) (PubMed).
: "p21-Activated kinase 4 promotes prostate cancer progression through CREB." dans: Oncogene, Vol. 32, Issue 19, pp. 2475-82, (2013) (PubMed).
: "p21-activated kinase 4 regulates ovarian cancer cell proliferation, migration, and invasion and contributes to poor prognosis in patients." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 43, pp. 18622-7, (2010) (PubMed).
: "Pak4, a novel Gab1 binding partner, modulates cell migration and invasion by the Met receptor." dans: Molecular and cellular biology, Vol. 29, Issue 11, pp. 3018-32, (2009) (PubMed).
: "Cdc42- and Rac1-mediated endothelial lumen formation requires Pak2, Pak4 and Par3, and PKC-dependent signaling." dans: Journal of cell science, Vol. 121, Issue Pt 7, pp. 989-1001, (2008) (PubMed).
: "p21-Activated kinase 5 (Pak5) localizes to mitochondria and inhibits apoptosis by phosphorylating BAD." dans: Molecular and cellular biology, Vol. 23, Issue 16, pp. 5526-39, (2003) (PubMed).
: "p21-activated protein kinase 4 (PAK4) interacts with the keratinocyte growth factor receptor and participates in keratinocyte growth factor-mediated inhibition of oxidant-induced cell death." dans: The Journal of biological chemistry, Vol. 278, Issue 12, pp. 10374-80, (2003) (PubMed).
: "p21-activated kinases: three more join the Pak." dans: The international journal of biochemistry & cell biology, Vol. 34, Issue 7, pp. 713-7, (2002) (PubMed).
Synonymes et noms alternatifs relatifs à PAK4
p21 (RAC1) activated kinase 4 (PAK4), p21 protein (Cdc42/Rac)-activated kinase 4 (Pak4), p21 (RAC1) activated kinase 4 (Pak4), p21 protein (Cdc42/Rac)-activated kinase 4 (pak4), 5730488L07Rik, AW555722, im:5916170, mKIAA1142, wu:fd12b01, zgc:92014Protein level used designations for PAK4
- PAK-4
- p21(CDKN1A)-activated kinase 4
- p21-activated kinase 4
- protein kinase related to S. cerevisiae STE20, effector for Cdc42Hs
- serine/threonine-protein kinase PAK 4
- p21 (CDKN1A)-activated kinase 4
- p21 protein (Cdc42/Rac)-activated kinase 4
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