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Paired Box Gene 2a Produits

(Paired Box Gene 2a (PAX2A))

Catégories

PAX2 encodes paired box gene 2, one of many human homologues of the Drosophila melanogaster gene prd. The central feature of this transcription factor gene family is the conserved DNA-binding paired box domain. PAX2 is believed to be a target of transcriptional supression by the tumor supressor gene WT1. Mutations within PAX2 have been shown to result in optic nerve colobomas and renal hypoplasia. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008].

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Catégories Paired Box Gene 2a en vedette

Paired Box Gene 2a Anticorps

High quality antibodies with extensive validation data.

Paired Box Gene 2a Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

Paired Box Gene 2a recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application ELISA, IHC, Coat, StM
Validations
  • (5)
N° du produit ABIN6940252
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC (p)
Validations
  • (3)
  • (4)
N° du produit ABIN562109
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, FACS
Validations
  • (4)
N° du produit ABIN7193593
Quantité 0.1 mg
Fiche technique Fiche technique

Paired Box Gene 2a recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6231710
Quantité 96 tests
Fiche technique Fiche technique

Paired Box Gene 2a recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1314063
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1314062
Quantité 25 μg
Fiche technique Fiche technique
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
N° du produit ABIN3133732
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits Paired Box Gene 2a

Yang, He, Peng, Zhong, Deng, Yu, Guan, Zuo, Xu: "Matrine suppresses the migration and invasion of NSCLC cells by inhibiting PAX2-induced epithelial-mesenchymal transition." dans: OncoTargets and therapy, Vol. 10, pp. 5209-5217, (2017) (PubMed).

Koehler, Mikosz, Molosh, Patel, Hashino: "Generation of inner ear sensory epithelia from pluripotent stem cells in 3D culture." dans: Nature, Vol. 500, Issue 7461, pp. 217-21, (2013) (PubMed).

Lancaster, Renner, Martin, Wenzel, Bicknell, Hurles, Homfray, Penninger, Jackson, Knoblich: "Cerebral organoids model human brain development and microcephaly." dans: Nature, Vol. 501, Issue 7467, pp. 373-9, (2013) (PubMed).

Palmieri, Gojis, Rudraraju, Stamp-Vincent, Wilson, Langdon, Gourley, Faratian: "Expression of steroid receptor coactivator 3 in ovarian epithelial cancer is a poor prognostic factor and a marker for platinum resistance." dans: British journal of cancer, Vol. 108, Issue 10, pp. 2039-44, (2013) (PubMed).

Albanito, Reddy, Musti: "c-Jun is essential for the induction of Il-1? gene expression in in vitro activated Bergmann glial cells." dans: Glia, Vol. 59, Issue 12, pp. 1879-90, (2012) (PubMed).

Viringipurampeer, Ferreira, DeMaria, Yoon, Shan, Moosajee, Gregory-Evans, Ngai, Gregory-Evans: "Pax2 regulates a fadd-dependent molecular switch that drives tissue fusion during eye development." dans: Human molecular genetics, Vol. 21, Issue 10, pp. 2357-69, (2012) (PubMed).

Doberstein, Pfeilschifter, Gutwein: "The transcription factor PAX2 regulates ADAM10 expression in renal cell carcinoma." dans: Carcinogenesis, Vol. 32, Issue 11, pp. 1713-23, (2011) (PubMed).

Lee, Doberstein, Baumgarten, Wieland, Ungerer, Bürger, Hardt, Boehncke, Pfeilschifter, Mihic-Probst, Mittelbronn, Gutwein: "PAX2 regulates ADAM10 expression and mediates anchorage-independent cell growth of melanoma cells." dans: PLoS ONE, Vol. 6, Issue 8, pp. e22312, (2011) (PubMed).

Muguruma, Nishiyama, Ono, Miyawaki, Mizuhara, Hori, Kakizuka, Obata, Yanagawa, Hirano, Sasai: "Ontogeny-recapitulating generation and tissue integration of ES cell-derived Purkinje cells." dans: Nature neuroscience, Vol. 13, Issue 10, pp. 1171-80, (2010) (PubMed).

Yu, Moriniere, Birke, Neumann, Fuchshofer, Kampik, Bloemendal, Welge-Lussen: "Reactivation of optic nerve head astrocytes by TGF-beta2 and H2O2 is accompanied by increased Hsp32 and Hsp47 expression." dans: Investigative ophthalmology & visual science, Vol. 50, Issue 4, pp. 1707-17, (2009) (PubMed).

Synonymes et noms alternatifs relatifs à Paired Box Gene 2a

paired box 2 (PAX2), paired box 2 (Pax2), paired box 2 L homeolog (pax2.L), paired box 2a (pax2a), paired box 2b (pax2b), cb378, noi, Opdc, PAPRS, Pax-2, pax-2, Pax-2a, pax-b, pax2, pax2.1, pax2.2, pax2a1, paxb, PAXZF-B, pax[zf-b], XPax-2, xPax-2a, XPax2

Protein level used designations for Paired Box Gene 2a

  • paired box homeotic gene 2
  • paired box protein Pax-2
  • optic disc coloboma
  • paired box gene 2
  • paired box protein Pax-2-A
  • no isthmus protein
  • paired box gene 2.1
  • paired box homeotic gene 2a
  • paired box protein Pax-2a
  • paired box 2b
  • paired box gene 2b
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