PAK3 Produits
(PAK3)
Catégories
PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. PAK proteins, a family of serine/threonine p21-activating kinases, serve as targets for the small GTP binding proteins Cdc42 and RAC and have been implicated in a wide range of biological activities. The protein encoded by this gene forms an activated complex with GTP-bound RAS-like (P21), CDC2 and RAC1 proteins which then catalyzes a variety of targets. This protein may be necessary for dendritic development and for the rapid cytoskeletal reorganization in dendritic spines associated with synaptic plasticity. Defects in this gene are the cause of non-syndromic mental retardation X-linked type 30 (MRX30), also called X-linked mental retardation type 47 (MRX47). Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].
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Catégories PAK3 en vedette
PAK3 Anticorps
High quality antibodies with extensive validation data.
PAK3 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
PAK3 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (1)
- (4)
N° du produit
ABIN518612
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human, Monkey
Application
WB, ELISA, IHC, FACS, ICC, Neut
Validations
- (4)
N° du produit
ABIN5611206
Quantité
0.1 mg
Fiche technique
Fiche technique
Reactivity
Human, Mouse
Application
WB, ELISA, IHC
Validations
- (5)
N° du produit
ABIN3028914
Quantité
0.4 mL
Fiche technique
Fiche technique
PAK3 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validations
N° du produit
ABIN1380787
Quantité
2 x 96 tests
Fiche technique
Fiche technique
PAK3 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Insect cells (Sf21)
Validations
- (2)
N° du produit
ABIN5570580
Quantité
5 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Insect cells (Sf9)
Validations
- (2)
N° du produit
ABIN5570579
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1313925
Quantité
10 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits PAK3
: "P21-Activated Kinase Inhibitors FRAX486 and IPA3: Inhibition of Prostate Stromal Cell Growth and Effects on Smooth Muscle Contraction in the Human Prostate." dans: PLoS ONE, Vol. 11, Issue 4, pp. e0153312, (2016) (PubMed).: "A 14-3-3? dimer-based scaffold bridges CtBP1-S/BARS to PI(4)KIII? to regulate post-Golgi carrier formation." dans: Nature cell biology, Vol. 14, Issue 4, pp. 343-54, (2012) (PubMed).
: "Gene diversity patterns at 10 X-chromosomal loci in humans and chimpanzees." dans: Molecular biology and evolution, Vol. 20, Issue 8, pp. 1281-9, (2003) (PubMed).
Synonymes et noms alternatifs relatifs à PAK3
p21 (RAC1) activated kinase 3 (PAK3), p21 protein (Cdc42/Rac)-activated kinase 3 (Pak3), p21 (RAC1) activated kinase 3 (Pak3), p21 protein (Cdc42/Rac)-activated kinase 3 L homeolog (pak3.L), beta-PAK, bPAK, bpak, CDKN1A, cdkn1a, hPAK3, MRX30, mrx30, MRX47, mrx47, OPHN3, ophn3, PAK-3, pak3, pak3-A, PAK3beta, pak3beta, Pak65alpha, Pak65beta, Stk4, XPak3Protein level used designations for PAK3
- PAK-3
- beta-PAK
- oligophrenin-3
- p21 (CDKN1A)-activated kinase 3
- p21-activated kinase 3
- serine/threonine-protein kinase PAK 3
- CDC42/RAC effector kinase PAK-B
- p21/Cdc42/Rac1-activated kinase 3 (yeast Ste20-related)
- p65-PAK
- PAK3a protein
- PAK3d protein
- serine/threonine protein kinase (p21-activated kinase 3)
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