PAK1/2/3 Produits
(P21-Activated Kinases 1/2/3 (PAK1/2/3))
Catégories
This gene encodes a family member of serine/threonine p21-activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2010].
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Catégories PAK1/2/3 en vedette
PAK1/2/3 Anticorps
High quality antibodies with extensive validation data.
PAK1/2/3 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
IHC, ELISA, WB
Validations
- (3)
N° du produit
ABIN7180065
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
IHC, ELISA, WB
Validations
- (4)
N° du produit
ABIN1847964
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
IHC, ELISA, IF
Validations
- (2)
N° du produit
ABIN7138850
Quantité
100 μL
Fiche technique
Fiche technique
PAK1/2/3 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validations
N° du produit
ABIN1380246
Quantité
2 x 96 tests
Fiche technique
Fiche technique
Dernières publications sur nos produits PAK1/2/3
: "P21-activated kinase 1 regulates resistance to BRAF inhibition in human cancer cells." dans: Molecular carcinogenesis, Vol. 56, Issue 5, pp. 1515-1525, (2017) (PubMed).: "Very-low and low-density lipoproteins induce neutral lipid accumulation and impair migration in monocyte subsets." dans: Scientific reports, Vol. 6, pp. 20038, (2016) (PubMed).
: "Spatially distinct binding of Cdc42 to PAK1 and N-WASP in breast carcinoma cells." dans: Molecular and cellular biology, Vol. 25, Issue 5, pp. 1680-95, (2005) (PubMed).
: "VE-cadherin regulates endothelial actin activating Rac and increasing membrane association of Tiam." dans: Molecular biology of the cell, Vol. 13, Issue 4, pp. 1175-89, (2002) (PubMed).
: "P21-activated kinase-1 phosphorylates and transactivates estrogen receptor-alpha and promotes hyperplasia in mammary epithelium." dans: The EMBO journal, Vol. 21, Issue 20, pp. 5437-47, (2002) (PubMed).
: "Affecting long-term fear memory formation through optical control of Rac1 GTPase and PAK activity in lateral amygdala." dans: Scientific reports, Vol. 7, Issue 1, pp. 13930 (PubMed).
Synonymes et noms alternatifs relatifs à PAK1/2/3
p21 protein (Cdc42/Rac)-activated kinase 1 S homeolog (pak1.S), p21 (RAC1) activated kinase 1 (PAK1), pak, pak-1, pakalpha, X-PAK1, XPak1Protein level used designations for PAK1/2/3
- p21 GTPase-associated kinase 1
- p21-activated kinase 1
- p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast)
- putative CDKN1A-activated kinase 1
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