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anti-Rat (Rattus) CDX2 Anticorps:
anti-Human CDX2 Anticorps:
anti-Mouse (Murine) CDX2 Anticorps:
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Human Polyclonal CDX2 Primary Antibody pour IHC (p), IP - ABIN151575
Verzi, Hatzis, Sulahian, Philips, Schuijers, Shin, Freed, Lynch, Dang, Brown, Clevers, Liu, Shivdasani: TCF4 and CDX2, major transcription factors for intestinal function, converge on the same cis-regulatory regions. dans Proceedings of the National Academy of Sciences of the United States of America 2010
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Human Monoclonal CDX2 Primary Antibody pour FACS, ELISA - ABIN1724921
Lee, Vogt, Hsiao, Osunkoya: CDX-2 expression in malignant germ cell tumors of the testes, intratubular germ cell neoplasia, and normal seminiferous tubules. dans Tumour biology 2012
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Human Monoclonal CDX2 Primary Antibody pour ELISA, WB - ABIN1724918
Liu, Zhang, Zhan, Brock, Herman, Guo: CDX2 serves as a Wnt signaling inhibitor and is frequently methylated in lung cancer. dans Cancer biology & therapy 2012
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Human Monoclonal CDX2 Primary Antibody pour ELISA, WB - ABIN560320
Zulueta, Caretti, Signorelli, Dallolio, Trinchera: Transcriptional control of the B3GALT5 gene by a retroviral promoter and methylation of distant regulatory elements. dans FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2014
Cow (Bovine) Polyclonal CDX2 Primary Antibody pour WB - ABIN2777319
Saad, Cho, Silverman, Liu: Usefulness of Cdx2 in separating mucinous bronchioloalveolar adenocarcinoma of the lung from metastatic mucinous colorectal adenocarcinoma. dans American journal of clinical pathology 2004
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Human Polyclonal CDX2 Primary Antibody pour ELISA, WB - ABIN251330
Qualtrough, Hinoi, Fearon, Paraskeva: Expression of CDX2 in normal and neoplastic human colon tissue and during differentiation of an in vitro model system. dans Gut 2002
Human Monoclonal CDX2 Primary Antibody pour IHC (p), IHC - ABIN152122
Flisikowska, Merkl, Landmann, Eser, Rezaei, Cui, Kurome, Zakhartchenko, Kessler, Wieland, Rottmann, Schmid, Schneider, Kind, Wolf, Saur, Schnieke: A porcine model of familial adenomatous polyposis. dans Gastroenterology 2012
These results provide evidence that CDX2 plays an essential role in functional trophectoderm formation during primate embryonic development.
LEF-1 (Montrer LEF1 Anticorps) and CDX2 performed at least as well as beta-catenin (Montrer CTNNB1 Anticorps), if not better, as a diagnostic marker for pilomatrical carcinomas
Study indicates that CDX2 expression can predict lack of response to NAT (Montrer BRD2 Anticorps).
CDX2 is not an independent prognostic biomarker in colorectal cancer
This study characterized a new and original variant of the CDX2 homeobox (Montrer Lbx1 Anticorps) gene.
CDX2 is highly expressed along the atrophic gastritis-metaplasia-dysplasia-cancer sequential. Though CDX2 expression is quite dominant in IM ( intestinal metaplasia), but its expression is not associated with H. pylori (Helicobacter pylori) infection.
of CDX2 using a hypoxia-inducible hTERT promoter-driven vector suppressed malignant progression of colon cancer cells in vitro and in vivo.These results suggest that pLVX-5HRE-hTERTp-CDX2-3FLAG gene therapy may be a promising novel approach to treat colon cancer
The results of the present study show that a lack of CDX2 expression in metastatic colorectal cancer is an adverse prognostic feature and a potential negative predictor of the response to chemotherapy.
We may conclude that hTERT promotes GIM by up-regulating CDX2 via NF-kappaB (Montrer NFKB1 Anticorps) signaling pathway.
Our work suggests that combination of the consensual CMS (Montrer Cd2ap Anticorps) classification and lack of CDX2 expression could be a useful marker to identify CMS4/CDX2-negative patients with a very poor prognosis
AMPK (Montrer PRKAA1 Anticorps) enhances intestinal barrier function and epithelial differentiation via promoting CDX2 expression, which is partially mediated by altered histone modifications in the Cdx2 promoter.
Data show that SLC7A7 (Montrer Slc7a7 Anticorps) is a CDX2 target gene, and that CDX2 binds directly to the SLC7A7 (Montrer Slc7a7 Anticorps) promoter.
these results provide further insight into the functional diversity of CDX2 in early mammalian embryos.
showed novel molecular regulation of CDX2 on Oct4 (Montrer POU5F1 Anticorps), and provided important clues for clarifying the mechanism of interaction between CDX2 and Oct4 (Montrer POU5F1 Anticorps) in embryo of mammals other than mouse
Results reveal an early regulatory switch in Cdx2 expression and show that different inputs are needed to drive Cdx2 expression in the blastocyst trophectoderm and in trophoblast stem cells.
CDX2(Null)/BRAF (Montrer BRAF Anticorps)(V600E) expression in adult mouse intestinal epithelium led to serrated morphology tumors (including carcinomas) and BRAF (Montrer BRAF Anticorps)(V600E) potently interacted with CDX2 silencing to alter gene expression. Like human serrated lesions, CDX2(Null)/BRAF (Montrer BRAF Anticorps)(V600E)-mutant epithelium expressed gastric markers.
including Wnt (Montrer WNT2 Anticorps) and Fgf pathway components active in the axial progenitor niche. Our data demonstrate that integration of the Cdx (Montrer CDX1 Anticorps)/Hox (Montrer MSH2 Anticorps) and T Brachyury (Montrer TBX1 Anticorps) transcriptional networks controls differential axial growth during vertebrate trunk elongation
A new organ culture system for adult murine oesophagus is described. Using this, Cdx2 and HNF4alpha (Montrer HNF4A Anticorps) were ectopically expressed by adenoviral infection. We demonstrate the expression of CDX2 and HNF4alpha (Montrer HNF4A Anticorps) in human biopsy samples.
Cdx (Montrer CDX1 Anticorps) members interact with the SWI (Montrer SMARCA1 Anticorps)-SNF (Montrer SNRPA Anticorps) complex and make direct contact with Brg1 (Montrer SMARCA4 Anticorps), a catalytic member of SWI (Montrer SMARCA1 Anticorps)-SNF (Montrer SNRPA Anticorps). Both Cdx2 and Brg1 (Montrer SMARCA4 Anticorps) co-occupy a number of Cdx (Montrer CDX1 Anticorps) target genes, and both factors are necessary for transcriptional regulation of such targets. Finally, Cdx2 and Brg1 (Montrer SMARCA4 Anticorps) occupancy occurs coincident with chromatin remodeling at some of these loci.
The authors identify a Cdx2-responsive segment of HoxA, immediately 5' to the recently defined regulatory domain orchestrating initial transcription of the first Hox (Montrer MSH2 Anticorps) gene.
Cdx1 (Montrer CDX1 Anticorps)-Cdx2 double null mutants exhibited loss of primitive erythroblasts, aberrant vascular remodelling of the yolk sac (Montrer ADCY10 Anticorps) and a block in hematopoietic differentiation from yolk sac (Montrer ADCY10 Anticorps)-derived cells in culture.
this study shows that Aloe vera (Montrer IGF2BP3 Anticorps) gel suppresses colitis-related colon carcinogenesis via increased expression of CDX-2, a tumor suppressor in colorectal cancer
Results point out the complex interplay between the DSB DNA repair activity and the homeoproteins HoxB7 (Montrer HOXB7 Anticorps) and Cdx2 in colon cancer cells.
results thus indicate that CDX2 is not required for TE formation during bovine development; nevertheless, it is necessary for maintaining TE integrity.
This gene is a member of the caudal-related homeobox transcription factor gene family. The encoded protein is a major regulator of intestine-specific genes involved in cell growth an differentiation. This protein also plays a role in early embryonic development of the intestinal tract. Aberrant expression of this gene is associated with intestinal inflammation and tumorigenesis.
caudal type homeobox 2
, caudal type homeobox transcription factor 2
, caudal type homeo box transcription factor 2
, homeobox protein CDX-2
, caudal-type homeobox protein 2
, caudal type homeo box 2
, caudal-type homeobox transcription factor 2