This is a synthetic peptide designed for use in combination with anti-IKBA Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
NFKBIA
Reactivité: Humain, Souris, Porc, Boeuf (Vache), Mouton, Rat, Singe
Hôte: Synthetic
BP
Indications d'application
Each Investigator should determine their own optimal working dilution for specific applications.
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Concentration
1 mg/mL
Buffer
Final peptide concentration is 1 mg/mL in PBS.
Conseil sur la manipulation
Avoid repeated freeze-thaw cycles.
Stock
-20 °C
Stockage commentaire
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Antigène
NFKBIA
(Nuclear Factor of kappa Light Polypeptide Gene Enhancer in B-Cells Inhibitor, alpha (NFKBIA))
Synonymes
IKBA Peptide, MAD-3 Peptide, NFKBI Peptide, AI462015 Peptide, Nfkbi Peptide, RL/IF-1 Peptide, ECI-6/IKBA Peptide, NFKBIA Peptide, ikbaB Peptide, wu:fb81f08 Peptide, zgc:56666 Peptide, zgc:77616 Peptide, ikbaA Peptide, wu:fj16a07 Peptide, zgc:85769 Peptide, NFKB inhibitor alpha Peptide, nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha Peptide, nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b Peptide, nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a Peptide, NFKBIA Peptide, Nfkbia Peptide, nfkbiab Peptide, nfkbiaa Peptide
Sujet
This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease.