RNA Binding Motif Protein 8A (RBM8A) (N-Term) Peptide
RBM8A
Reactivité: Humain, Rat
Hôte: Synthetic
BP, WB
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- Antigène Tous les produits RBM8A
- RBM8A (RNA Binding Motif Protein 8A (RBM8A))
- Protein Region
- N-Term
- Origine
- Humain, Rat
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Séquence
- EDFAMDEDGD ESIHKLKEKA KKRKGRGFGS EEGSRARMRE DYDSVEQDGD
- Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-Rbm8a Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Antigène
- RBM8A (RNA Binding Motif Protein 8A (RBM8A))
- Synonymes
- BOV-1A Peptide, BOV-1B Peptide, BOV-1C Peptide, C1DELq21.1 Peptide, DEL1q21.1 Peptide, MDS014 Peptide, RBM8 Peptide, RBM8B Peptide, TAR Peptide, Y14 Peptide, ZNRP Peptide, ZRNP1 Peptide, 2310057C03Rik Peptide, AA673428 Peptide, Rbm8 Peptide, RBM8A Peptide, rbm8 Peptide, rbm8a Peptide, rnp-5 Peptide, fb34f03 Peptide, wu:fb34f03 Peptide, zgc:110525 Peptide, rbm8-A Peptide, rbm8a-A Peptide, rbm8-B Peptide, RNA binding motif protein 8A Peptide, RNA binding motif protein 8a Peptide, RNA binding motif protein 8A S homeolog Peptide, RNA binding motif protein 8A L homeolog Peptide, RBM8A Peptide, Rbm8a Peptide, rbm8a Peptide, rbm8a.S Peptide, rbm8a.L Peptide
- Sujet
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Rbm8a is a component of a splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of a few core proteins and several more peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Core components of the EJC, that remains bound to spliced mRNAs throughout all stages of mRNA metabolism, functions to mark the position of the exon-exon junction in the mature mRNA and thereby influences downstream processes of gene expression including mRNA splicing, nuclear mRNA export, subcellular mRNA localization, translation efficiency and nonsense-mediated mRNA decay (NMD). The heterodimer MAGOH-RBM8A interacts with PYM that function to enhance the translation of EJC-bearing spliced mRNAs by recruiting them to the ribosomal 48S preinitiation complex.
Alias Symbols: Rbm8
Protein Size: 174 - Poids moléculaire
- 19 kDa
- ID gène
- 295284
- NCBI Accession
- XM_215637, XP_215637
- UniProt
- Q27W01
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