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Iodotyrosine Deiodinase (IYD) (N-Term) Peptide

IYD Reactivité: Humain Hôte: Synthetic BP, WB
N° du produit ABIN1541609
  • Antigène Tous les produits IYD
    IYD (Iodotyrosine Deiodinase (IYD))
    Protein Region
    N-Term
    Origine
    Humain
    Source
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Séquence
    NADRSMEKKK GEPRTRAEAR PWVDEDLKDS SDLHQAEEDA DEWQESEENV
    Attributs du produit
    This is a synthetic peptide designed for use in combination with anti-IYD Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Indications d'application
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Antigène
    IYD (Iodotyrosine Deiodinase (IYD))
    Synonymes
    MGC85450 Peptide, C6orf71 Peptide, DEHAL1 Peptide, TDH4 Peptide, dJ422F24.1 Peptide, 0610009A07Rik Peptide, AI265638 Peptide, Dehal1 Peptide, RGD1309288 Peptide, IYD-1 Peptide, iodotyrosine deiodinase Peptide, iodotyrosine deiodinase L homeolog Peptide, IYD Peptide, iyd.L Peptide, iyd Peptide, Iyd Peptide
    Sujet
    This gene encodes an enzyme that catalyzes the oxidative NADPH-dependent deiodination of mono- and diiodotyrosine, which are the halogenated byproducts of thyroid hormone production. The N-terminus of the protein functions as a membrane anchor. Mutations in this gene cause congenital hypothyroidism due to dyshormonogenesis type 4, which is also referred to as deiodinase deficiency, or iodotyrosine dehalogenase deficiency, or thyroid hormonogenesis type 4.

    Alias Symbols: C6orf71, DEHAL1, TDH4, dJ422F24.1

    Protein Size: 247
    Poids moléculaire
    27 kDa
    ID gène
    389434
    NCBI Accession
    NM_001164695, NP_001158167
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