P21-Activated Kinase 4 (PAK4) (Middle Region) Peptide
PAK4
Reactivité: Humain
Hôte: Synthetic
BP, WB
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- Antigène Tous les produits PAK4
- PAK4 (P21-Activated Kinase 4 (PAK4))
- Protein Region
- Middle Region
- Origine
- Humain
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Séquence
- EPQLAPPACT PAAPAVPGPP GPRSPQREPQ RVSHEQFRAA LQLVVDPGDP
- Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-PAK4 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Conseil sur la manipulation
- Avoid repeat freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Antigène
- PAK4 (P21-Activated Kinase 4 (PAK4))
- Synonymes
- 5730488L07Rik Peptide, AW555722 Peptide, mKIAA1142 Peptide, im:5916170 Peptide, wu:fd12b01 Peptide, zgc:92014 Peptide, p21 (RAC1) activated kinase 4 Peptide, p21 protein (Cdc42/Rac)-activated kinase 4 Peptide, PAK4 Peptide, Pak4 Peptide, pak4 Peptide
- Sujet
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PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3 and PAK4. PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. They serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK4 interacts specifically with the GTP-bound form of Cdc42Hs and weakly activates the JNK family of MAP kinases. PAK4 is a mediator of filopodia formation and may play a role in the reorganization of the actin cytoskeleton. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Alias Symbols: -
Protein Size: 591 - Poids moléculaire
- 65 kDa
- ID gène
- 10298
- NCBI Accession
- NM_005884, NP_005875
- UniProt
- O96013
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