Tumor Necrosis Factor, alpha-Induced Protein 1 (Endothelial) (TNFAIP1) (C-Term) Peptide
TNFAIP1
Reactivité: Humain, Rat
Hôte: Synthetic
BP, WB
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- Antigène Tous les produits TNFAIP1
- TNFAIP1 (Tumor Necrosis Factor, alpha-Induced Protein 1 (Endothelial) (TNFAIP1))
- Protein Region
- C-Term
- Origine
- Humain, Rat
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Séquence
- LNVLLYETPR VPDNSLLEAT SRSRSQASPS EDEDTFELRD RVRRIHVKRY
- Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-Tnfaip1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Conseil sur la manipulation
- Avoid repeat freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Antigène
- TNFAIP1 (Tumor Necrosis Factor, alpha-Induced Protein 1 (Endothelial) (TNFAIP1))
- Synonymes
- zgc:55302 Peptide, wu:fi06b02 Peptide, TNFAIP1 Peptide, B12 Peptide, B61 Peptide, BTBD34 Peptide, EDP1 Peptide, hBACURD2 Peptide, Edp-1 Peptide, Edp1 Peptide, Tnfip1 Peptide, tumor necrosis factor, alpha-induced protein 1 (endothelial) Peptide, TNF alpha induced protein 1 Peptide, TNF alpha induced protein 1 L homeolog Peptide, tnfaip1 Peptide, TNFAIP1 Peptide, Tnfaip1 Peptide, tnfaip1.L Peptide
- Sujet
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Tnfaip1 is a substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in regulation of cytoskeleton structure. The BCR(BACURD2) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome, thereby regulating the actin cytoskeleton and cell migration. Its interaction with RHOB may regulate apoptosis.
Alias Symbols: Edp1
Protein Size: 316 - Poids moléculaire
- 34 kDa
- ID gène
- 287543
- NCBI Accession
- NM_182950, NP_891995
- UniProt
- Q7TNY1
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