Ring Finger Protein 216 (RNF216) (N-Term) Peptide
RNF216
Reactivité: Humain, Souris
Hôte: Synthetic
BP, WB
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- Antigène Tous les produits RNF216
- RNF216 (Ring Finger Protein 216 (RNF216))
- Protein Region
- N-Term
- Origine
- Humain, Souris
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Séquence
- IVNPRLEQKV IILGENGLLF PESEPLEVQN QSSEDSETEL LSNPGEPAAS
- Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-Rnf216 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Conseil sur la manipulation
- Avoid repeat freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Antigène
- RNF216 (Ring Finger Protein 216 (RNF216))
- Synonymes
- RGD1565135 Peptide, TRIAD3 Peptide, RNF216 Peptide, zin Peptide, u7i1 Peptide, triad3 Peptide, ubce7ip1 Peptide, MGC147026 Peptide, 2810055g22rik Peptide, 2810055G22Rik Peptide, AI647468 Peptide, AU019462 Peptide, C86502 Peptide, F830018F18Rik Peptide, UIP83 Peptide, Ubce7ip1 Peptide, CAHH Peptide, U7I1 Peptide, UBCE7IP1 Peptide, ZIN Peptide, ring finger protein 216 Peptide, Rnf216 Peptide, RNF216 Peptide, rnf216 Peptide
- Sujet
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Rnf216 acts as an E3 ubiquitin ligase, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and then transfers it to substrates promoting their degradation by the proteasome. It promotes degradation of TRAF3, TLR4 and TLR9. It contributes to the regulation of antiviral responses. It down-regulates activation of NF-kappa-B, IRF3 activation and IFNB production and promotes TNF and RIP mediated apoptosis.
Protein Size: 853 - Poids moléculaire
- 93 kDa
- ID gène
- 108086
- UniProt
- P58283
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