G Protein Pathway Suppressor 2 (GPS2) (C-Term) Peptide
GPS2
Reactivité: Humain
Hôte: Synthetic
BP, WB
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- Antigène Tous les produits GPS2
- GPS2 (G Protein Pathway Suppressor 2 (GPS2))
- Protein Region
- C-Term
- Origine
- Humain
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Séquence
- TAQPPPHYGP TQPAYSPSQQ LRAPSAFPAV QYLSQPQPQP YAVHGHFQPT
- Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-GPS2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Stock
- -20 °C
- Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Antigène
- GPS2 (G Protein Pathway Suppressor 2 (GPS2))
- Synonymes
- gps2 Peptide, MGC68832 Peptide, MGC63588 Peptide, zgc:63588 Peptide, GPS2 Peptide, MGC133909 Peptide, amf-1 Peptide, AMF-1 Peptide, AI505953 Peptide, G protein pathway suppressor 2 Peptide, G protein pathway suppressor 2 L homeolog Peptide, gps2 Peptide, gps2.L Peptide, GPS2 Peptide, Gps2 Peptide
- Sujet
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This gene encodes a protein involved in G protein-mitogen-activated protein kinase (MAPK) signaling cascades. When overexpressed in mammalian cells, this gene could potently suppress a RAS- and MAPK-mediated signal and interfere with JNK activity, suggesting that the function of this gene may be signal repression. The encoded protein is an integral subunit of the NCOR1-HDAC3 (nuclear receptor corepressor 1-histone deacetylase 3) complex, and it was shown that the complex inhibits JNK activation through this subunit and thus could potentially provide an alternative mechanism for hormone-mediated antagonism of AP1 (activator protein 1) function.
Alias Symbols: GPS2,
Protein Size: 327 - ID gène
- 2874
- NCBI Accession
- XP_005256674
- UniProt
- Q13227
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