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Tumor Necrosis Factor alpha (TNF alpha) (C-Term) Peptide

TNF alpha Reactivité: Humain Hôte: Synthetic BP, WB
N° du produit ABIN5511930
  • Antigène Tous les produits TNF alpha
    TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))
    Protein Region
    C-Term
    Origine
    Humain
    Source
    • 5
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Séquence
    AVSYQTKVNL LSAIKSPCQR ETPEGAEAKP WYEPIYLGGV FQLEKGDRLS
    Attributs du produit
    This is a synthetic peptide designed for use in combination with anti-TNFA Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Stock
    -20 °C
    Stockage commentaire
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Antigène
    TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))
    Synonymes
    DIF Peptide, TNF-alpha Peptide, TNFA Peptide, TNFSF2 Peptide, RATTNF Peptide, Tnfa Peptide, tnf Peptide, TNF-a Peptide, TNFalpha Peptide, Tnfsf1a Peptide, TNFa Peptide, cTNF Peptide, Tnf-alpha Peptide, tnfa-like Peptide, TNF-ALPHA Peptide, dif Peptide, tnfa Peptide, xtnf Peptide, tnfsf2 Peptide, tnf-alpha Peptide, Cachectin Peptide, tumor necrosis factor Peptide, tumor necrosis factor b (TNF superfamily, member 2) Peptide, tumor necrosis factor alpha Peptide, tumor necrosis factor a (TNF superfamily, member 2) Peptide, TNF Peptide, Tnf Peptide, tnf Peptide, tnfb Peptide, tnf-alpha Peptide, LOC103694380 Peptide, tnfa Peptide
    Sujet
    This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine.

    Alias Symbols: TNF,TNFA,TNFSF2,

    Protein Size: 233
    ID gène
    7124
    NCBI Accession
    NP_000585
    UniProt
    P01375
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