Integrin alpha M (ITGAM) (C-Term) Peptide
ITGAM
Reactivité: Humain
Hôte: Synthetic
BP, WB
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- Antigène Tous les produits CD11b (ITGAM)
- CD11b (ITGAM) (Integrin alpha M (ITGAM))
- Protein Region
- C-Term
- Origine
- Humain
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Séquence
- PFEVPNPLPL IVGSSVGGLL LLALITAALY KLGFFKRQYK DMMSEGGPPG
- Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-ITGAM Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Integrin alpha M (ITGAM) peptide
ITGAM Reactivité: Humain, Chien, Souris, Rat Hôte: Synthetic BP, Imm
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Stock
- -20 °C
- Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Antigène
- CD11b (ITGAM) (Integrin alpha M (ITGAM))
- Synonymes
- CD11b/CD18 Peptide, CR3 Peptide, CR3A Peptide, Cd11b Peptide, F730045J24Rik Peptide, Ly-40 Peptide, MAC1 Peptide, Mac-1 Peptide, Mac-1a Peptide, CD11B Peptide, MAC-1 Peptide, MAC1A Peptide, MO1A Peptide, SLEB6 Peptide, C3bi Peptide, integrin subunit alpha M Peptide, integrin alpha M Peptide, integrin, alpha M (complement component 3 receptor 3 subunit) Peptide, integrin alpha-M Peptide, ITGAM Peptide, Itgam Peptide, LOC100351865 Peptide
- Sujet
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This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: CR3A, MO1A, CD11B, MAC-1, MAC1A, SLEB6
Protein Size: 1152 - ID gène
- 3684
- NCBI Accession
- NM_000632, NP_000623
- UniProt
- P11215
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