X-Linked Inhibitor of Apoptosis (XIAP) (Middle Region) Peptide
XIAP
Reactivité: Humain
Hôte: Synthetic
BP, WB
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- Antigène Tous les produits XIAP
- XIAP (X-Linked Inhibitor of Apoptosis (XIAP))
- Protein Region
- Middle Region
- Origine
- Humain
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Séquence
- GGGLTDWKPS EDPWEQHAKW YPGCKYLLEQ KGQEYINNIH LTHSLEECLV
- Attributs du produit
- This is a synthetic peptide designed for use in combination with anti- XIAP Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Stock
- -20 °C
- Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Antigène
- XIAP (X-Linked Inhibitor of Apoptosis (XIAP))
- Synonymes
- API3 Peptide, BIRC4 Peptide, IAP-3 Peptide, ILP1 Peptide, MIHA Peptide, XLP2 Peptide, hIAP-3 Peptide, hIAP3 Peptide, api3 Peptide, birc4 Peptide, ilp1 Peptide, miha Peptide, xlp2 Peptide, xxiap Peptide, 1110015C02Rik Peptide, Aipa Peptide, Api3 Peptide, Birc4 Peptide, IAP3 Peptide, ILP-1 Peptide, mXIAP Peptide, riap3 Peptide, fb73d01 Peptide, wu:fb73d01 Peptide, zgc:91873 Peptide, BIRC8 Peptide, X-linked inhibitor of apoptosis Peptide, X-linked inhibitor of apoptosis L homeolog Peptide, XIAP Peptide, xiap Peptide, xiap.L Peptide, Xiap Peptide
- Sujet
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This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-apoptotic function. This protein functions through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 and inhibits apoptosis induced by menadione, a potent inducer of free radicals, and interleukin 1-beta converting enzyme. This protein also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7. Mutations in this gene are the cause of X-linked lymphoproliferative syndrome. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 2 and 11.
Alias Symbols: API3, ILP1, MIHA, XLP2, BIRC4, IAP-3, hIAP3, hIAP-3
Protein Size: 497 - ID gène
- 331
- NCBI Accession
- NM_001167, NP_001158
- UniProt
- P98170
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