Stomatin (EPB72)-Like 2 (STOML2) (Middle Region) Peptide
STOML2
Reactivité: Humain
Hôte: Synthetic
WB, BP
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- Antigène Tous les produits STOML2
- STOML2 (Stomatin (EPB72)-Like 2 (STOML2))
- Protein Region
- Middle Region
- Origine
- Humain
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Source
- Synthetic
- Application
- Western Blotting (WB), Blocking Peptide (BP)
- Séquence
- LRIMDPYKAS YGVEDPEYAV TQLAQTTMRS ELGKLSLDKV FRERESLNAS
- Attributs du produit
- This is a synthetic peptide designed for use in combination with anti- STOML2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Stock
- -20 °C
- Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Antigène
- STOML2 (Stomatin (EPB72)-Like 2 (STOML2))
- Synonymes
- zgc:63505 Peptide, MGC116533 Peptide, 0610038F01Rik Peptide, MSLP2 Peptide, SLP-2 Peptide, stomatin (EPB72)-like 2 Peptide, stomatin like 2 Peptide, stomatin like 2 L homeolog Peptide, stomatin (Epb7.2)-like 2 Peptide, stoml2 Peptide, STOML2 Peptide, stoml2.L Peptide, Stoml2 Peptide
- Sujet
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Mitochondrial protein that probably regulates the biogenesis and the activity of mitochondria. Stimulates cardiolipin biosynthesis, binds cardiolipin-enriched membranes where it recruits and stabilizes some proteins including prohibitin and may therefore act in the organization of functional microdomains in mitochondrial membranes. Through regulation of the mitochondrial function may play a role into several biological processes including cell migration, cell proliferation, T-cell activation, calcium homeostasis and cellular response to stress. May play a role in calcium homeostasis through negative regulation of calcium efflux from mitochondria. Required for mitochondrial hyperfusion a pro-survival cellular response to stress which results in increased ATP production by mitochondria. May also regulate the organization of functional domains at the plasma membrane and play a role in T-cell activation through association with the T-cell receptor signaling complex and its regulation.
Alias Symbols: SLP-2, HSPC108
Protein Size: 356 - ID gène
- 30968
- NCBI Accession
- NM_001287031, NP_001273961
- UniProt
- Q9UJZ1
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