PPP2R1B
Reactivité: Humain, Rat, Singe, Souris, Porc
Hôte: Synthetic
BP
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Stock
-20 °C
Stockage commentaire
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Antigène
PPP2R1B
(Protein Phosphatase 2, Regulatory Subunit A, beta (PPP2R1B))
Synonymes
2410091N08Rik Peptide, AI790395 Peptide, PP2A-Abeta Peptide, PR65B Peptide, protein phosphatase 2, regulatory subunit A, beta Peptide, protein phosphatase 2 scaffold subunit Abeta Peptide, protein phosphatase 2 scaffold subunit A beta Peptide, protein phosphatase 2 regulatory subunit A, beta S homeolog Peptide, Ppp2r1b Peptide, PPP2R1B Peptide, ppp2r1b.S Peptide
Sujet
This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes a beta isoform of the constant regulatory subunit A. Mutations in this gene have been associated with some lung and colon cancers. Alternatively spliced transcript variants have been described.