Mitogen-Activated Protein Kinase 9 (MAPK9) (C-Term) Peptide
MAPK9
Reactivité: Humain
Hôte: Synthetic
WB
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- Antigène Tous les produits JNK2 (MAPK9)
- JNK2 (MAPK9) (Mitogen-Activated Protein Kinase 9 (MAPK9))
- Protein Region
- C-Term
- Origine
- Humain
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Source
- Synthetic
- Application
- Western Blotting (WB)
- Séquence
- EVMDWEERSK NGVVKDQPSD AAVSSNATPS QSSSINDISS MSTEQTLASD
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Stock
- -20 °C
- Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Antigène
- JNK2 (MAPK9) (Mitogen-Activated Protein Kinase 9 (MAPK9))
- Synonymes
- MAPK9 Peptide, JNK-55 Peptide, JNK2 Peptide, JNK2A Peptide, JNK2ALPHA Peptide, JNK2B Peptide, JNK2BETA Peptide, PRKM9 Peptide, SAPK Peptide, SAPK1a Peptide, p54a Peptide, p54aSAPK Peptide, AI851083 Peptide, Prkm9 Peptide, JNK2-ALPHA1 Peptide, MAP kinase 9 Peptide, mitogen-activated protein kinase 9 Peptide, MAP kinase 9 Peptide, MAPK9 Peptide, Mapk9 Peptide, MPK9 Peptide
- Sujet
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The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase targets specific transcription factors, and thus mediates immediate-early gene expression in response to various cell stimuli. It is most closely related to MAPK8, both of which are involved in UV radiation induced apoptosis, thought to be related to the cytochrome c-mediated cell death pathway. This gene and MAPK8 are also known as c-Jun N-terminal kinases. This kinase blocks the ubiquitination of tumor suppressor p53, and thus it increases the stability of p53 in nonstressed cells. Studies of this gene's mouse counterpart suggest a key role in T-cell differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported.
Alias Symbols: JNK2, SAPK, p54a, JNK2A, JNK2B, PRKM9, JNK-55, SAPK1a, JNK2BETA, p54aSAPK, JNK2ALPHA
Protein Size: 167 - ID gène
- 5601
- NCBI Accession
- NM_001135044, NP_001128516
- UniProt
- P45984
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