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Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A) (Middle Region) Peptide

GADD45A Reactivité: Humain Hôte: Synthetic BP, WB
N° du produit ABIN5672545
  • Antigène Tous les produits GADD45A
    GADD45A (Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A))
    Protein Region
    Middle Region
    Origine
    Humain
    Source
    • 2
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Séquence
    LLLLETDAGP AASEGAEQPP DLHCVLVTNP HSSQWKDPAL SQLICFCRES
    Attributs du produit
    This is a synthetic peptide designed for use in combination with anti- GADD45A Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Stock
    -20 °C
    Stockage commentaire
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Antigène
    GADD45A (Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A))
    Synonymes
    MGC53491 Peptide, zgc:91795 Peptide, gadd45a Peptide, GADD45A Peptide, ddit1 Peptide, gadd45 Peptide, GADD45 Peptide, AA545191 Peptide, Ddit1 Peptide, DDIT1 Peptide, Gadd45 Peptide, growth arrest and DNA damage inducible alpha L homeolog Peptide, growth arrest and DNA-damage-inducible, alpha, b Peptide, growth arrest and DNA damage inducible alpha Peptide, growth arrest and DNA damage-inducible protein 45 Peptide, growth arrest and DNA-damage-inducible 45 alpha Peptide, growth arrest and DNA-damage-inducible, alpha Peptide, gadd45a.L Peptide, gadd45ab Peptide, GADD45A Peptide, gadd45a Peptide, GADD45 Peptide, Gadd45a Peptide
    Sujet
    This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of this gene is mediated by both p53-dependent and -independent mechanisms. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

    Alias Symbols: DDIT1, GADD45

    Protein Size: 131
    ID gène
    1647
    NCBI Accession
    NM_001199741, NP_001186670
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