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phospholipase C, gamma 1 (PLCG1) (N-Term) Peptide

PLCG1 Reactivité: Humain Hôte: Synthetic BP, WB
N° du produit ABIN5673550
  • Antigène Tous les produits Phospholipase C gamma 1 (PLCG1)
    Phospholipase C gamma 1 (PLCG1) (phospholipase C, gamma 1 (PLCG1))
    Protein Region
    N-Term
    Origine
    Humain
    Source
    • 5
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Séquence
    DKIEGAIDIR EIKEIRPGKT SRDFDRYQED PAFRPDQSHC FVILYGMEFR
    Attributs du produit
    This is a synthetic peptide designed for use in combination with anti- PLCG1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Stock
    -20 °C
    Stockage commentaire
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Antigène
    Phospholipase C gamma 1 (PLCG1) (phospholipase C, gamma 1 (PLCG1))
    Synonymes
    NCKAP3 Peptide, PLC-II Peptide, PLC1 Peptide, PLC148 Peptide, PLCgamma1 Peptide, plc1 Peptide, nckap3 Peptide, plc-ii Peptide, plc148 Peptide, plcgamma1 Peptide, PPLCA Peptide, AI894140 Peptide, Cded Peptide, Plc-1 Peptide, Plc-gamma1 Peptide, Plcg-1 Peptide, fj46f04 Peptide, wu:fj46f04 Peptide, wu:fj57a05 Peptide, phospholipase C gamma 1 Peptide, phospholipase C gamma 1 L homeolog Peptide, 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 Peptide, phospholipase C, gamma 1 Peptide, PLCG1 Peptide, plcg1.L Peptide, LOC100633163 Peptide, Plcg1 Peptide, plcg1 Peptide
    Sujet
    The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene.

    Alias Symbols: PLC1, NCKAP3, PLC-II, PLC148, PLCgamma1

    Protein Size: 1290
    ID gène
    5335
    NCBI Accession
    NM_002660, NP_002651
    UniProt
    P19174
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