seryl-tRNA Synthetase 2, Mitochondrial (SARS2) (Middle Region) Peptide
SARS2
Reactivité: Humain
Hôte: Synthetic
BP, WB
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- Antigène Tous les produits SARS2
- SARS2 (seryl-tRNA Synthetase 2, Mitochondrial (SARS2))
- Protein Region
- Middle Region
- Origine
- Humain
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Séquence
- LEIGEKLDII RQKRLSHVSG HRSYYLRGAG ALLQHGLVNF TFNKLLRRGF
- Attributs du produit
- This is a synthetic peptide designed for use in combination with anti- SARS2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Stock
- -20 °C
- Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Antigène
- SARS2 (seryl-tRNA Synthetase 2, Mitochondrial (SARS2))
- Synonymes
- 2410015F05Rik Peptide, D7Ertd353e Peptide, SerRS Peptide, SerRSmt Peptide, SARS Peptide, SARSM Peptide, SERS Peptide, SYS Peptide, mtSerRS Peptide, seryl-aminoacyl-tRNA synthetase 2 Peptide, seryl-tRNA synthetase 2, mitochondrial Peptide, Sars2 Peptide, SARS2 Peptide
- Sujet
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This gene encodes the mitochondrial seryl-tRNA synthethase precursor, a member of the class II tRNA synthetase family. The mature enzyme catalyzes the ligation of Serine to tRNA(Ser) and participates in the biosynthesis of selenocysteinyl-tRNA(sec) in mitochondria. The enzyme contains an N-terminal tRNA binding domain and a core catalytic domain. It functions in a homodimeric form, which is stabilized by tRNA binding. This gene is regulated by a bidirectional promoter that also controls the expression of mitochondrial ribosomal protein S12. Both genes are within the critical interval for the autosomal dominant deafness locus DFNA4 and might be linked to this disease. Multiple transcript variants encoding different isoforms have been identified for this gene.
Alias Symbols: SYS, SARS, SERS, SARSM, SerRS, SerRSmt, mtSerRS
Protein Size: 518 - ID gène
- 54938
- NCBI Accession
- NM_001145901, NP_001139373
- UniProt
- Q9NP81
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