A synthetic peptide for use as a blocking control in assays to test for specificity of KLB antibody, Alternative Names: Klotho Beta control peptide, Klotho Beta antibody Blocking Peptide, Anti-Klotho Beta Blocking Peptide, KLB Blocking Peptide, BKL Blocking Peptide, MGC142213 Blocking Peptide
KLB is a single-pass type III membrane protein. It contributes to the transcriptional repression of cholesterol 7-alpha-hydroxylase (CYP7A1), the rate-limiting enzyme in bile acid synthesis. KLB is probably inactive as a glycosidase. It increases the ability of FGFR1 and FGFR4 to bind FGF21.