TNF Receptor Superfamily, Member 6 (FAS) Peptide
FAS
Reactivité: Mammifères
Hôte: Synthetic
BP, WB, IHC
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- Antigène Tous les produits FAS
- FAS (TNF Receptor Superfamily, Member 6 (FAS))
- Type de proteíne
- Synthetic
- Origine
- Mammifères
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Séquence
- GLHHDGQFCH KPCPPGERKA RDCTVNGDEP DCVPCQEGKE YTDKAHFSSK
- Attributs du produit
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A synthetic peptide for use as a blocking control in assays to test for specificity of FAS antibody,
Alternative Names: FAS control peptide, FAS antibody Blocking Peptide, Anti-FAS Blocking Peptide, Fas, TNF receptor superfamily, member 6 Blocking Peptide, ALPS1A Blocking Peptide, APO-1 Blocking Peptide, APT1 Blocking Peptide, CD95 Blocking Peptide, FAS1 Blocking Peptide, FASTM Blocking Peptide, TNFRSF6 Blocking Peptide
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- Indications d'application
- Optimal conditions should be determined by the investigator
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
- Buffer
- PBS
- Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20 °C long term.
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- Antigène
- FAS (TNF Receptor Superfamily, Member 6 (FAS))
- Synonymes
- ALPS1A Peptide, APO-1 Peptide, APT1 Peptide, CD95 Peptide, FAS1 Peptide, FASTM Peptide, TNFRSF6 Peptide, AI196731 Peptide, APO1 Peptide, TNFR6 Peptide, Tnfrsf6 Peptide, lpr Peptide, Fas cell surface death receptor Peptide, Fas (TNF receptor superfamily member 6) Peptide, FAS Peptide, Fas Peptide, fas Peptide
- Sujet
- FAS is a member of the TNF-receptor superfamily. This receptor contains a death domain. It has been shown to play a central role in the physiological regulation of programmed cell death, and has been implicated in the pathogenesis of various malignancies and diseases of the immune system. The interaction of this receptor with its ligand allows the formation of a death-inducing signaling complex that includes Fas-associated death domain protein (FADD), caspase 8, and caspase 10. The autoproteolytic processing of the caspases in the complex triggers a downstream caspase cascade, and leads to apoptosis. This receptor has been also shown to activate NF-kappaB, MAPK3/ERK1, and MAPK8/JNK, and is found to be involved in transducing the proliferating signals in normal diploid fibroblast and T cells. At least eight alternatively spliced transcript variants encoding seven distinct isoforms have been described.
- Poids moléculaire
- 36 kDa
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