Activin A Receptor, Type IIB (ACVR2B) Peptide
ACVR2B
Reactivité: Humain
Hôte: Synthetic
BP, WB
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- Antigène Tous les produits ACVR2B
- ACVR2B (Activin A Receptor, Type IIB (ACVR2B))
- Origine
- Humain
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-ACVR2B antibody (Catalog #: ARP45043_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Antigène
- ACVR2B (Activin A Receptor, Type IIB (ACVR2B))
- Synonymes
- ACVR2B Peptide, XAR1 Peptide, actr-iib Peptide, actriib Peptide, ACTRIIB Peptide, ActR-IIB Peptide, HTX4 Peptide, ActRIIB Peptide, actr2b Peptide, actrIIb Peptide, wu:fj97d11 Peptide, activin A receptor type 2B Peptide, activin A receptor type 2B L homeolog Peptide, activin A receptor type 2Ba Peptide, activin receptor IIB Peptide, ACVR2B Peptide, acvr2b Peptide, acvr2b.L Peptide, Acvr2b Peptide, acvr2ba Peptide
- Sujet
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Activin receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling, and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases. ACVR2B is activin A type IIB receptor, which displays a 3- to 4-fold higher affinity for the ligand than activin A type II receptor.
Alias Symbols: HTX4, ACTRIIB, ActR-IIB
Protein Interaction Partner: ACVR1B,BMP2,BMP7,GDF11,GDF5,IGSF1,INHBA,INHBB,INHBC,MSTN,SNX1,SNX2,SNX6,SYNJ2BP,TGFBRAP1,ACVR1B,BMP6,BMP7,ENG,GDF5,INHBA,INHBB,MSTN,SNX1,SNX2,SNX6,SYNJ2BP
Protein Size: 303 - Poids moléculaire
- 33 kDa
- ID gène
- 93
- NCBI Accession
- NM_001106
- UniProt
- Q4VAU9
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