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Amphiregulin (AREG) (Middle Region) Peptide

AREG Reactivité: Humain Hôte: Synthetic BP, WB
N° du produit ABIN973365
  • Antigène Tous les produits Amphiregulin (AREG)
    Amphiregulin (AREG)
    Protein Region
    Middle Region
    Origine
    Humain
    Source
    • 1
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Séquence
    PQIPGYIVDD SVRVEQVVKP PQNKTESENT SDKPKRKKKG GKNGKNRRNR
    Attributs du produit
    This is a synthetic peptide designed for use in combination with anti-AREG Antibody(ARP30233_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Indications d'application
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Antigène
    Amphiregulin (AREG)
    Synonymes
    AR Peptide, CRDGF Peptide, SDGF Peptide, Sdgf Peptide, AREG Peptide, AREGB Peptide, AREG/SDGF Peptide, amphiregulin Peptide, AREG Peptide, Areg Peptide
    Sujet
    The protein encoded by this gene is a member of the epidermal growth factor family. It is an autocrine growth factor as well as a mitogen for astrocytes, Schwann cells, and fibroblasts. It is related to epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha). This protein interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells and inhibits the growth of certain aggressive carcinoma cell lines. This encoded protein is associated with a psoriasis-like skin phenotype.

    Alias Symbols: AR, AREGB, CRDGF, MGC13647, SDGF

    Protein Interaction Partner: CCND3,EGFR,MMP9,UBQLN4,WT1,EGFR

    Protein Size: 252
    Poids moléculaire
    28 kDa
    ID gène
    374
    NCBI Accession
    NM_001657, NP_001648
    UniProt
    P15514
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