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Activating Transcription Factor 4 (Tax-Responsive Enhancer Element B67) (ATF4) Peptide

ATF4 Reactivité: Humain Hôte: Synthetic BP, WB
N° du produit ABIN973549
  • Antigène Tous les produits ATF4
    ATF4 (Activating Transcription Factor 4 (Tax-Responsive Enhancer Element B67) (ATF4))
    Origine
    Humain
    Source
    • 8
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Attributs du produit
    This is a synthetic peptide designed for use in combination with anti-ATF4 antibody (Catalog #: P100913_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Indications d'application
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Antigène
    ATF4 (Activating Transcription Factor 4 (Tax-Responsive Enhancer Element B67) (ATF4))
    Synonymes
    CREB-2 Peptide, CREB2 Peptide, TAXREB67 Peptide, TXREB Peptide, ATF4 Peptide, atf-4 Peptide, creb-2 Peptide, creb2 Peptide, taxreb67 Peptide, txreb Peptide, atf4 Peptide, wu:fj01c08 Peptide, wu:fk30b04 Peptide, zgc:85951 Peptide, sb:eu681 Peptide, wu:fb08f07 Peptide, zgc:171702 Peptide, Atf-4 Peptide, C/ATF Peptide, ATF4-I Peptide, atf4-a Peptide, atf4-b Peptide, atf4-ii Peptide, activating transcription factor 4 Peptide, activating transcription factor 4 L homeolog Peptide, activating transcription factor 4a Peptide, activating transcription factor 4b Peptide, activating transcription factor 4 S homeolog Peptide, ATF4 Peptide, atf4 Peptide, Atf4 Peptide, atf4.L Peptide, atf4a Peptide, atf4b Peptide, atf4.S Peptide
    Sujet
    ATF4s a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain. Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromsome at q28 in a region containing a large inverted duplication.This gene encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain. Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromsome at q28 in a region containing a large inverted duplication.

    Alias Symbols: CREB-2, CREB2, TAXREB67, TXREB

    Protein Interaction Partner: DISC1,DISC1,TRIB3,CCDC106,CEBPB,CEBPG,CREBZF,DAPK3,DDIT3,DISC1,GABBR2,GPS2,GTF2F2,JUN,LDOC1,NFE2L1,NFE2L2,POLR2C,PTCD3,TREX2,TRIB3,TTR,ATF3,CCDC106,CREBBP,Cebpb,DISC1,EIF2A,GABBR1,GABBR2,GPS2,GTF2B,GTF2F2,JUN,LDOC1,POLR2C,PTCD3,TBP,TREX2,TRIB3,TTR

    Protein Size: 351
    Poids moléculaire
    38 kDa
    ID gène
    468
    NCBI Accession
    NM_001675, NP_001666
    UniProt
    P18848
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