BCL2-Like 1 (BCL2L1) (N-Term) Peptide
BCL2L1
Reactivité: Humain
Hôte: Synthetic
BP, WB
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- Antigène Tous les produits BCL2L1
- BCL2L1 (BCL2-Like 1 (BCL2L1))
- Protein Region
- N-Term
- Origine
- Humain
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-BCL2L1 antibody (Catalog #: AVARP02002_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Antigène
- BCL2L1 (BCL2-Like 1 (BCL2L1))
- Synonymes
- BCL-XL/S Peptide, BCL2L Peptide, BCLX Peptide, BCLXL Peptide, BCLXS Peptide, Bcl-X Peptide, PPP1R52 Peptide, bcl-xL Peptide, bcl-xS Peptide, Bcl(X)L Peptide, Bcl-XL Peptide, Bcl-Xs Peptide, Bcl2l Peptide, BclX Peptide, bcl-x Peptide, Bcl-xl Peptide, Bclx Peptide, bcl-X Peptide, Bcl-xL Peptide, BCL-XL Peptide, BCL2L1 Peptide, bcl-XL Peptide, bcl-x(l) Peptide, bcl-xl/s Peptide, bcl-xs Peptide, bcl2l Peptide, bclx Peptide, bclxl Peptide, xR11 Peptide, bcl-xl Peptide, blp1 Peptide, cb1021 Peptide, zfBLP1 Peptide, BCL2 like 1 Peptide, BCL2-like 1 Peptide, Bcl2-like 1 Peptide, BCL2-like 1 L homeolog Peptide, bcl2-like 1 Peptide, BCL2L1 Peptide, Bcl2l1 Peptide, bcl2l1 Peptide, bcl2l1.L Peptide
- Sujet
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BCL2L1 encodes a protein which belongs to the BCL-2 protein family. The proteins encoded by BCL2L1 are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Two alternatively spliced transcript variants, which encode distinct isoforms, have been reported. The longer isoform acts as an apoptotic inhibitor and the shorter form acts as an apoptotic activator.
Alias Symbols: BCL-XL/S, BCL2L, BCLX, Bcl-X, DKFZp781P2092, bcl-xL, bcl-xS, BCLXL, BCLXS, PPP1R52
Protein Interaction Partner: CRYAA,CRYAB,BAD,BAD,BAD,BAX,BAX,BAX,BBC3,BBC3,BBC3,BCL2L11,BCL2L11,BID,BID,BID,BID,BID,BIK,BIK,BMF,BMF,HRK,HRK,HRK,MOAP1,RTN1,RTN4,TP53,TPT1,ANTXR1,APAF1,AVEN,BAD,BAG1,BAK1,BAX,BBC3,BCAP31,BCL2,BCL2L1,BCL2L10,BCL2L11,BCL2L12,BCL2L14,BCLAF1,BECN1,BID,BIK,BMF,BNIP1,BNIP3,BNIP3L,CAPN1,CASP1,CASP8,CASP9,CFLAR,CRYAA,CRYAB,CYCS,FKBP8,HRK,IKZF3,IRS1,IRS2,MAPK8,MCL1,MOAP1,NLRP1,PMAIP1,PPP1CA,PSEN1,PSEN2,RAD9A,RTN1,RTN4,SIVA1,SNCA,SPNS1,TMBIM6,TP53,VDAC1,APAF1,AVEN,BAD,BAK1,BAX,BBC3,BCAP31,BCL2,BCL2L11,BCL2L14,BECN1,BID,BIK,BLK,BNIP1,BNIP3,BNIPL,Bcl2l11,CASP2,CASP8,CASP9,CFLAR,CFLAR,CYCS,DYNLL1,FKBP8,HRK,IKZF3,IRS1,MCL1,MOAP1,PGAM5,PMAIP1,PPP1CA,PSEN1,PSEN2,RAD9A,RAF1,RTN1,RTN4,SPNS1,VDAC1
Protein Size: 233 - Poids moléculaire
- 26 kDa
- ID gène
- 598
- NCBI Accession
- NM_138578, NP_612815
- UniProt
- Q07817
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