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CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA) Peptide

CEBPA Reactivité: Humain Hôte: Synthetic BP, WB
N° du produit ABIN974816
  • Antigène Tous les produits CEBPA
    CEBPA (CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA))
    Origine
    Humain
    Source
    • 4
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Attributs du produit
    This is a synthetic peptide designed for use in combination with anti-CEBPA antibody (Catalog #: P100908_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Indications d'application
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Antigène
    CEBPA (CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA))
    Synonymes
    C/EBP-alpha Peptide, CEBP Peptide, C/ebpalpha Peptide, CBF-A Peptide, Cebp Peptide, DBPCEP Peptide, c/ebpa Peptide, cb1062 Peptide, wu:fj20f03 Peptide, C/EBP Peptide, C/EBPalpha Peptide, xC/EBP Peptide, cC/EBP Peptide, C/EBP alpha Peptide, CCAAT/enhancer binding protein alpha Peptide, CCAAT/enhancer binding protein (C/EBP), alpha Peptide, CCAAT/enhancer binding protein alpha L homeolog Peptide, CEBPA Peptide, Cebpa Peptide, cebpa Peptide, cebpa.L Peptide
    Sujet
    CEBPA is a bZIP transcription factor which can bind as a homodimer to certain promoters and enhancers. It can also form heterodimers with the related proteins CEBP-beta and CEBP-gamma. It has been shown to bind to the promoter and modulate the expression of the gene encoding leptin, a protein that plays an important role in body weight homeostasis. Also, CEBPA can interact with CDK2 and CDK4, thereby inhibiting these kinases and causing growth arrest in cultured cells.

    Alias Symbols: CEBP, C/EBP-alpha

    Protein Interaction Partner: LTF,NCOA6,PIAS1,ATF2,CDK2,CDK4,CDKN1A,CDKN3,CDX1,CEBPA,CEBPB,CEBPD,CREBBP,CTNNB1,DBP,EP300,GATA2,GSK3B,HNF1A,MSX2,MYC,NCOA6,NFYA,NR3C1,PIAS1,RB1,RBL1,RFC1,RUNX1,SOX10,SOX8,SPI1,SUMO3,AR,ATF2,Atf2,CDK2,CDK4,CEBPB,CTNNB1,ESR1,MAPK8,MSX2,MYC,NCOA6,NR3C1,RARB,SMAD3,SMAD4,SPI1,UBC

    Protein Size: 358
    Poids moléculaire
    38 kDa
    ID gène
    1050
    NCBI Accession
    NM_004364, NP_004355
    UniProt
    P49715
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