Collagen, Type I, alpha 2 (COL1A2) (Middle Region) Peptide
COL1A2
Reactivité: Humain
Hôte: Synthetic
BP, WB
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- Antigène Tous les produits COL1A2
- COL1A2 (Collagen, Type I, alpha 2 (COL1A2))
- Protein Region
- Middle Region
- Origine
- Humain
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-COL1A2 antibody (Catalog #: ARP58441_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Antigène
- COL1A2 (Collagen, Type I, alpha 2 (COL1A2))
- Synonymes
- AA960264 Peptide, AI325291 Peptide, Col1a-2 Peptide, Cola-2 Peptide, Cola2 Peptide, oim Peptide, OI4 Peptide, Gas-6 Peptide, alpha2(I) Peptide, hm:zehn2357 Peptide, wu:fa98d05 Peptide, wu:fa99g10 Peptide, wu:fb04c08 Peptide, wu:fb11d06 Peptide, zehn2357 Peptide, coagulation factor II, thrombin Peptide, collagen, type I, alpha 2 Peptide, collagen type I alpha 2 chain Peptide, collagen type I alpha 2 L homeolog Peptide, growth arrest specific 6 Peptide, F2 Peptide, Col1a2 Peptide, col1a2.L Peptide, COL1A2 Peptide, Gas6 Peptide, col1a2 Peptide
- Sujet
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COL1A2 is the pro-alpha2 chain of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIB, recessive Ehlers-Danlos syndrome Classical type, idiopathic osteoporosis, and atypical Marfan syndrome. Symptoms associated with mutations in this gene, however, tend to be less severe than mutations in the gene for the alpha1 chain of type I collagen (COL1A1) reflecting the different role of alpha2 chains in matrix integrity.This gene encodes the pro-alpha2 chain of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIB, recessive Ehlers-Danlos syndrome Classical type, idiopathic osteoporosis, and atypical Marfan syndrome. Symptoms associated with mutations in this gene, however, tend to be less severe than mutations in the gene for the alpha1 chain of type I collagen (COL1A1) reflecting the different role of alpha2 chains in matrix integrity. Three transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: OI4
Protein Interaction Partner: APP,BGN,CD36,CD44,CD93,COL5A3,DCN,FN1,ITGA2,ITGA2B,ITGB3,LUM,MMP9,MYOC,P4HB,SHBG,SPARC,TGFBI,VWF
Protein Size: 1366 - Poids moléculaire
- 150 kDa
- ID gène
- 1278
- NCBI Accession
- NM_000089, NP_000080
- UniProt
- P08123
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