Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1) (C-Term) Peptide
CTNNB1
Reactivité: Humain
Hôte: Synthetic
BP, WB, ChIP
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- Antigène Tous les produits CTNNB1
- CTNNB1 (Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1))
- Protein Region
- C-Term
- Origine
- Humain
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Chromatin Immunoprecipitation (ChIP)
- Séquence
- LGLDIGAQGE PLGYRQDDPS YRSFHSGGYG QDALGMDPMM EHEMGGHHPG
- Attributs du produit
- This is a synthetic peptide designed for use in combination with anti-CTNNB1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Indications d'application
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
- Stock
- -20 °C
- Stockage commentaire
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Antigène
- CTNNB1 (Catenin (Cadherin-Associated Protein), beta 1, 88kDa (CTNNB1))
- Synonymes
- Jup Peptide, LOC100217813 Peptide, CTNNB1 Peptide, CTNNB Peptide, Bfc Peptide, Catnb Peptide, Mesc Peptide, ctnnb Peptide, id:ibd2058 Peptide, wu:fb73e10 Peptide, wu:fi81c06 Peptide, wu:fk25h01 Peptide, ctnnb1 Peptide, CHBCAT Peptide, MRD19 Peptide, armadillo Peptide, beta-catenin Peptide, catenin beta 1 Peptide, catenin (cadherin associated protein), beta 1 Peptide, catenin (cadherin-associated protein), beta 1 Peptide, catenin beta 1 S homeolog Peptide, catenin beta 1 L homeolog Peptide, CTNNB1 Peptide, Ctnnb1 Peptide, ctnnb1 Peptide, ctnnb1.S Peptide, ctnnb1.L Peptide
- Sujet
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The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Three transcript variants encoding the same protein have been found for this gene.
Alias Symbols: CTNNB, DKFZp686D02253, FLJ25606, FLJ37923
Protein Size: 781 - Poids moléculaire
- 85 kDa
- ID gène
- 1499
- NCBI Accession
- NM_001904, NP_001895
- UniProt
- P35222
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