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Chemokine (C-X-C Motif) Receptor 6 (CXCR6) Peptide

CXCR6 Reactivité: Humain Hôte: Synthetic BP, WB
N° du produit ABIN975480
  • Antigène Tous les produits CXCR6
    CXCR6 (Chemokine (C-X-C Motif) Receptor 6 (CXCR6))
    Origine
    Humain
    Source
    • 5
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Attributs du produit
    This is a synthetic peptide designed for use in combination with anti-CXCR6 antibody (Catalog #: AVARP07030_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Indications d'application
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Antigène
    CXCR6 (Chemokine (C-X-C Motif) Receptor 6 (CXCR6))
    Synonymes
    BONZO Peptide, CD186 Peptide, STRL33 Peptide, TYMSTR Peptide, BB217514 Peptide, C-X-C motif chemokine receptor 6 Peptide, chemokine (C-X-C motif) receptor 6 L homeolog Peptide, chemokine (C-X-C motif) receptor 6 Peptide, CXCR6 Peptide, cxcr6.L Peptide, Cxcr6 Peptide
    Sujet
    CXCR6 is a receptor for the C-X-C chemokine CXCL16. It is used as a coreceptor by SIVs and by strains of HIV-2 and m-tropic HIV-1.The CXCR6/AKT/mTOR pathway plays a central role in the development of prostate cancer. CXCR6 and CXCR3 act coordinately with respective ligands and are involved in the pathophysiology of Juvenile Idiopathic Arthritis-associated inflammatory processes. The CXCL16-CXCR6-system express in human schwannomas of different localization and in malignant peripheral nerve sheath tumors. The protein may play an important role in the retention of T cells within the lung.

    Alias Symbols: BONZO, CD186, STRL33, TYMSTR

    Protein Interaction Partner: CXCL16

    Protein Size: 342
    Poids moléculaire
    39 kDa
    ID gène
    10663
    NCBI Accession
    NM_006564, NP_006555
    UniProt
    O00574
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