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Desmocollin 3 (DSC3) (N-Term) Peptide

DSC3 Reactivité: Humain Hôte: Synthetic BP, WB
N° du produit ABIN976006
  • Antigène Tous les produits Desmocollin 3 (DSC3)
    Desmocollin 3 (DSC3)
    Protein Region
    N-Term
    Origine
    Humain
    Source
    • 2
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Attributs du produit
    This is a synthetic peptide designed for use in combination with anti-DSC3 antibody (Catalog #: ARP45195_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Indications d'application
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Conseil sur la manipulation
    Avoid repeated freeze-thaw cycles.
    Stock
    -20 °C
    Stockage commentaire
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Antigène
    Desmocollin 3 (DSC3)
    Synonymes
    CDHF3 Peptide, DSC Peptide, DSC1 Peptide, DSC2 Peptide, DSC4 Peptide, HT-CP Peptide, 5430426I24Rik Peptide, MGC85083 Peptide, desmocollin 3 Peptide, desmocollin 3 S homeolog Peptide, DSC3 Peptide, Dsc3 Peptide, dsc3.S Peptide, dsc3 Peptide
    Sujet
    DSC3 is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined. Alternative splicing results in two transcript variants encoding distinct isoforms.The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined. Alternative splicing results in two transcript variants encoding distinct isoforms.

    Alias Symbols: CDHF3, DSC, DSC1, DSC2, DSC4, HT-CP

    Protein Interaction Partner: PKP3,PKP3,CTNNB1,JUP,PKP3,PKP4,CTNNB1,JUP,PKP3,PKP4

    Protein Size: 896
    Poids moléculaire
    85 kDa
    ID gène
    1825
    NCBI Accession
    NM_001941, NP_001932
    UniProt
    Q14574
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